2,4,5-Trichlorobenzoyl chloride CAS 42221-49-8
| CAS No. | 42221-49-8 |
| Molecular Formula | C7H2Cl4O |
| Molecular Weight | 243.90 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2,4,5-Trichlorobenzoyl chloride is closely related to a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2,4,5-Trichlorobenzoyl chloride (CAS 42221-49-8) is a high-purity analytical reference standard with the molecular formula C7H2Cl4O and a molecular weight of 243.90 g/mol.
The molecular framework of 2,4,5-Trichlorobenzoyl chloride (C7H2Cl4O) is characterized by a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H2Cl4O |
| Molecular Weight | 243.90 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1969 |
| Halogen Content | Cl-containing |
Related Trichlorobenzoyl Standards
Recommended Standards
- 3,5-dibromo-1-(trideuteriomethyl)-1,2,4-triazole (CAS 2226642-22-2)
- 4,5-Dibromo-2-(methyl-d3)-2H-1,2,3-triazole (CAS 2306333-09-3)
- 2,3,4,5-Tetrachlorobenzaldehyde (CAS 56962-16-4)
- 2,5-Dibromo-1,3,4-thiadiazole (CAS 55981-29-8)
- 5-Bromo-3-(trifluoroacetyl)indole (CAS 32387-18-1)
- tert-Butyl 4-[6-(3-bromophenyl)-3-cyanopyridin-2-yl]piperazine-1-carboxylate (CAS 946385-57-5)
- Poly[oxy(methyl-1,2-ethanediyl)], .alpha.,.alpha.',.alpha.''-1,2,6-hexanetriyltris[.omega.-hydroxy- (CAS 9072-61-1)
- 8-Chloro-1-cyclopropyl-7-(3,5-dimethylpiperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 103481-72-7)
- Salbutamol Impurity 192 (CAS CATO-C4X-1176192)
- 2-Piperazin-1-yl-3h-thieno[3,2-d]pyrimidin-4-one (CAS 1248559-72-9)
- Pyridine-2,4,6-triol (CAS 626-47-1)
- Cefuroxime Impurity 41 (CAS 75884-38-7)
- Alogliptin Impurity 49 (CAS 655-63-0)
- (Asp28)-Exenatide trifluoroacetate salt (CAS 1678417-24-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com