1-Acetyl-5-aminoindolin-2-one CAS 422518-10-3
| CAS No. | 422518-10-3 |
| Molecular Formula | C10H10N2O2 |
| Molecular Weight | 190.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 1-Acetyl-5-aminoindolin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
1-Acetyl-5-aminoindolin-2-one (CAS 422518-10-3) is a high-purity analytical reference standard with the molecular formula C10H10N2O2 and a molecular weight of 190.20 g/mol.
The molecular framework of 1-Acetyl-5-aminoindolin-2-one (C10H10N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H10N2O2 |
| Molecular Weight | 190.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
Related Acetyl Standards
- 1-(5-Aminoindolin-1-yl)propan-1-one (CAS 1017673-66-3)
- 1-(6-Aminoindolin-1-yl)propan-1-one (CAS 1018286-45-7)
- 1-(4-Aminoindolin-1-yl)propan-1-one (CAS 1368864-35-0)
- 2-(6-Aminoindolin-1-yl)acetamide (CAS 1019555-37-3)
- 2-(6-Aminoindolin-1-yl)ethan-1-ol (CAS 927684-70-6)
- (5-Aminoindolin-1-yl)(cyclopropyl)methanone (CAS 927996-72-3)
- (6-Aminoindolin-1-yl)(cyclopropyl)methanone (CAS 927996-96-1)
- 1-(4-Aminoindolin-1-yl)ethanone (CAS 17274-64-5)
Recommended Standards
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- 2-(4,5,6,7-Tetrahydro-2H-pyrazolo[4,3-c]pyridin-2-yl)ethan-1-ol hydrochloride (CAS 1612173-24-6)
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