Mesalazine Impurity 47 CAS 13300-63-5
| CAS No. | 13300-63-5 |
| Molecular Formula | C7H3Cl2NO4 |
| Molecular Weight | 236.01 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Mesalazine Impurity 47 (CAS 13300-63-5, C7H3Cl2NO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Mesalazine Impurity 47 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 236.01 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Mesalazine Impurity 47 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H3Cl2NO4 |
| Molecular Weight | 236.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1960 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Mesalazine Standards
- Mesalazine Impurity 54 (CAS CATO-C4X-132454)
- Mesalazine Impurity 28 (CAS 40038-46-8)
- Mesalazine EP Impurity I (CAS 3147-53-3)
- Mesalazine Impurity 53 (CAS CATO-C4X-132453)
- Mesalazine Impurity 50 (CAS CATO-C4X-132450)
- Mesalazine Impurity 45 (CAS CATO-C4X-132445)
- Mesalazine Impurity 30 (CAS 14474-22-7)
- Mesalazine Impurity 55 (CAS CATO-C4X-132455)
Recommended Standards
- 3511-90-8 4-bromanyl-2,3,5,6-tetrakis(fluoranyl)pyridine 4-bromo-2,3,5,6-tetrafluoropyridine A822581 (CAS 3511-90-8)
- Iodylbenzene (CAS 696-33-3)
- Chloroprocaine impurity 1 (CAS 22509-50-8)
- acetyl-4-iodo-1H-pyrazole (CAS 98027-52-2)
- Pemafibrate Impurity 12 (CAS CATO-C4X-290312)
- Lidocaine Impurity 31 (CAS 70336-49-1)
- Cefmetazole Impurity 56 (CAS CATO-C4X-150756)
- 5-(Bromomethyl)isoquinoline hydrobromide (CAS 586373-76-4)
- 3-bromoquinolin-5-amine (CAS 116632-57-6)
- 2-(3-methoxyphenyl)morpholine (CAS 1017395-60-6)
- 4-chloro-2-(2,2,2-trifluoroethoxy)aniline (CAS 186387-90-6)
- 2-(4-Sulfamoylphenoxy)acetamide (CAS 69986-22-7)
- 2-(1-(Tert-butoxycarbonyl)-2,2-dimethylpiperidin-4-ylidene)acetic acid (CAS 2163945-62-6)
- (β-Asp5)-Delta-Sleep Inducing Peptide (CAS 82602-88-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com