(1R,3S)-Tryptophan EP Impurity I CAS 42438-72-2
| CAS No. | 42438-72-2 |
| Molecular Formula | C13H14N2O2 |
| Molecular Weight | 230.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures (1R,3S)-Tryptophan EP Impurity I under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
(1R,3S)-Tryptophan EP Impurity I (CAS 42438-72-2) is a certified pharmaceutical impurity reference standard with the molecular formula C13H14N2O2 and a molecular weight of 230.26 g/mol.
Structurally, (1R,3S)-Tryptophan EP Impurity I (C13H14N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 230.26 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C13H14N2O2 |
| Molecular Weight | 230.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1969 |
| Nitrogen Atoms | 2 |
Recommended Standards
- (1H-indol-4-yl)(morpholino)methanone (CAS 65923-23-1)
- (1R,6S)-6-benzoylcyclohex-3-ene-1-carboxylic acid (CAS 35033-78-4)
- (1H-indol-3-yl)(morpholino)methanone (CAS 225782-55-8)
- (1S,3S)-Tryptophan EP Impurity I (CAS 40678-46-4)
- Vardenafil EP Impurity A (CAS 2169247-39-4)
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- Decitabine Impurity 3 (CAS 17117-72-5)
- 2,7-Dimethyl-2,7-octanediol (CAS 19781-07-8)
- 1-(4-methoxyphenyl)pyrimidine-2,4,6(1H,3H,5H)-trione (CAS 69457-35-8)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com