4-Fluoro-3-methoxybenzeneboronic acid pinacol ester, 97% CAS 425378-85-4
| CAS No. | 425378-85-4 |
| Molecular Formula | C13H18BFO3 |
| Molecular Weight | 252.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-Fluoro-3-methoxybenzeneboronic acid pinacol ester, 97% (CAS 425378-85-4), a certified reference material (molecular formula C13H18BFO3, MW 252.09 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 4-Fluoro-3-methoxybenzeneboronic acid pinacol ester, 97% is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 252.09 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H18BFO3 |
| Molecular Weight | 252.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
Related Fluoro Standards
- 3-Fluoro-4-(hydroxymethyl)phenylboronic Acid Pinacol Ester (CAS 1082066-29-2)
- 2-Fluoro-3-methoxyphenylboronic Acid Pinacol Ester (CAS 1165936-00-4)
- 2-(2-Fluoro-5-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1190129-83-9)
- (3-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanol (CAS 1314141-37-1)
- [4-Fluoro-3-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methanol (CAS 1333264-06-4)
- (2-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanol (CAS 1333264-07-5)
- (5-Fluoro-2-((4-methylpiperazin-1-yl)methyl)phenyl)boronic acid (CAS 1333387-98-6)
- (2-Fluoro-5-((4-methylpiperazin-1-yl)methyl)phenyl)boronic acid (CAS 1334173-43-1)
Recommended Standards
- 4-Fluoro-3-hydroxy-5-methylphenylboronic acid, pinacol ester (CAS 2121512-07-8)
- 4-Fluoro-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzene-1,2-diamine (CAS 2166096-64-4)
- 4-Fluoro-2-methoxybenzeneboronic acid pinacol ester, 97% (CAS 624741-83-9)
- 5-(Iodomethyl)-6-oxaspiro[3.4]octane (CAS 2138023-08-0)
- (1-Methyl-3-(trifluoromethyl)-5-((3-(trifluoromethyl)phenyl)sulfonyl)-1H-pyrazol-4-yl)methyl (4-chlorophenyl)carbamate (CAS 318469-25-9)
- Iohexol Impurity 13 (CAS 122731-74-2)
- 4-Chloro-2-iodoaniline, 97% (CAS 63069-48-7)
- Butyl Vinyl Ether (stabilized with Trihexylamine) (CAS 111-34-2)
- 25935-87-9 2-[(1,1-Dioxidotetrahydro-3-thienyl)oxy]ethanol DTXSID80395022 (CAS 25935-87-9)
- 3-Bromo-2-chloro-6-(methylthio)pyridine (CAS 1809158-14-2)
- Benzo[d]isothiazole-3(2H)-thione 1,1-dioxide (CAS 27148-03-4)
- 1,2,3,4-tetrahydropyridin-4-one (CAS 24681-60-5)
- 2-Azaspiro[4.6]undecane (CAS 184-14-5)
- Semaglutide impurity 80 (CAS CATO-C4X-222680)
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