4-Chloro-6-methoxypyrimidine-5-carbonitrile CAS 425394-86-1
| CAS No. | 425394-86-1 |
| Molecular Formula | C6H4ClN3O |
| Molecular Weight | 169.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-Chloro-6-methoxypyrimidine-5-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
4-Chloro-6-methoxypyrimidine-5-carbonitrile (CAS 425394-86-1), molecular formula C6H4ClN3O and molecular weight 169.57 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C6H4ClN3O, 4-Chloro-6-methoxypyrimidine-5-carbonitrile contains an amide group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 169.57 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C6H4ClN3O |
| Molecular Weight | 169.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 7-chloro-1H-pyrazolo[4,3-d]pyrimidin-5-amine (CAS 1086398-36-8)
- 2-Chloro-4-methoxypyrimidine-5-carbonitrile (CAS 1106295-93-5)
- 3-Chloro-[1,2,4]triazolo[4,3-b]pyridazin-6-amine (CAS 1150888-24-6)
- 7-Chloro-3H-imidazo[4,5-b]pyridine 4-oxide (CAS 115953-98-5)
- 7-Chloro-2-methyloxazolo[5,4-d]pyrimidine (CAS 118767-93-4)
- 3-Chloro-6-(hydroxymethyl)pyrazine-2-carbonitrile (CAS 1257072-48-2)
- 7-Chloro[1,2,4]triazolo[4,3-c]pyrimidin-5-amine (CAS 1306739-68-3)
- 5-Chloro-3-(furan-2-yl)-1H-1,2,4-triazole (CAS 1315346-11-2)
Recommended Standards
- 4-Chloro-5H-pyrrolo[2,3-d]pyrimidin-6(7H)-one (CAS 346599-63-1)
- 4-Chloropyridine-2,6-dicarbaldehyde (CAS 311767-65-4)
- 4-chloro-3-methyl-[1,2]oxazolo[5,4-d]pyrimidine (CAS 51850-60-3)
- 5-Chloro-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine (CAS 5899-92-3)
- 2-((2,6-Dichlorobenzyl)thio)-3-(furan-2-ylmethyl)-6,7-dimethoxyquinazolin-4(3H)-imine (CAS 477848-69-4)
- 2-(Azetidin-1-yl)pyridine (CAS 262352-58-9)
- tert-Butyl (5-(hydroxymethyl)-1H-pyrazol-3-yl)carbamate (CAS 352533-21-2)
- 1-(2,4-Dichlorophenyl)cyclopropanemethanamine (CAS 771582-72-0)
- 3,5-Difluoro-2-hydroxybenzoic acid (CAS 84376-20-5)
- m-PEG16-SH (CAS 874820-38-9)
- 4-(4,6,8-Trimethylimidazo[1,5-a]pyrimidin-2-yl)morpholine (CAS 88896-76-8)
- 3-Methyl-4-(thiophen-2-yl)butan-2-ol (CAS 1249323-62-3)
- 7-Chloro-5-fluoro-2-({[4-(trifluoromethyl)phenyl]methyl}sulfanyl)-1,3-benzoxazole (CAS 866010-51-7)
- Met(O)14-Exenatide trifluoroacetate salt (CAS 1678417-38-3)
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