2-(1,3-Benzodioxol-5-yl-6-Fluoro-3-Hydroxy-4H-Chromen-4-One CAS 4257-54-9
| CAS No. | 4257-54-9 |
| Molecular Formula | C16H9FO5 |
| Molecular Weight | 300.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 2-(1,3-Benzodioxol-5-yl-6-Fluoro-3-Hydroxy-4H-Chromen-4-One under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
2-(1,3-Benzodioxol-5-yl-6-Fluoro-3-Hydroxy-4H-Chromen-4-One (CAS 4257-54-9) is a high-purity analytical reference standard with the molecular formula C16H9FO5 and a molecular weight of 300.24 g/mol.
The molecular framework of 2-(1,3-Benzodioxol-5-yl-6-Fluoro-3-Hydroxy-4H-Chromen-4-One (C16H9FO5) is characterized by a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C16H9FO5 |
| Molecular Weight | 300.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | F-containing |
Related Benzodioxol Standards
- 3-(2H-1,3-benzodioxol-4-yl)propanoic acid (CAS 20974-68-9)
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- N-(1,3-Benzodioxol-5-ylmethyl)-N-(4,6-dimethylpyrimidin-2-yl)guanidine (CAS 675142-99-1)
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Recommended Standards
- 1-(4-Methoxyphenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carbohydrazide (CAS 618090-93-0)
- 2-(3-(Cyclohexylmethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2096333-64-9)
- 1-(2-Methoxyphenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carbohydrazide (CAS 618091-02-4)
- 2-(4-(Cyclohexylmethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2096339-40-9)
- 2,5-Dihydroxy-N1,N1,N4,N4-tetramethylterephthalamide (CAS 20877-00-3)
- 4-Methyl-[1,4]bipiperidinyl dihydrochloride (CAS 3543-23-5)
- 4-Bromo-2-(4-methoxyphenoxy)thiazole (CAS 1065074-21-6)
- Amcinonide (CAS 51022-69-6)
- 3'-(Benzyloxy)-[1,1'-biphenyl]-3-carboxylic acid (CAS 893736-29-3)
- 7-Fluoro-6-methoxyquinoline-3-carbonitrile (CAS 1452855-40-1)
- 1O8B70QB9P 53101-49-8 6-Hydroxy-2,5,7,8-tetramethyl-chroman-2-carboxylic acid, (+)- UNII-1O8B70QB9P 2H-1-Benzopyran-2-carboxylic acid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-, (2R)- 2H-1-Benzopyran-2-carboxylic acid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-, (R)- (+)-6-Hydroxy-2,5,7,8-tetramethyl-chroman-2-carboxylic acid (R)-(+)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (R)-Trolox (CAS 53101-49-8)
- 2-Fluoro-3-(trifluoromethoxy)phenol (CAS 1334164-87-2)
- 1-(4-(4-(Thiophen-3-yl)thiazol-2-yl)piperazin-1-yl)but-2-en-1-one (CAS 1448140-56-4)
- Semaglutide Impurity 144 (CAS 394210-59-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com