1O8B70QB9P 53101-49-8 6-Hydroxy-2,5,7,8-tetramethyl-chroman-2-carboxylic acid, (+)- UNII-1O8B70QB9P 2H-1-Benzopyran-2-carboxylic acid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-, (2R)- 2H-1-Benzopyran-2-carboxylic acid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-, (R)- (+)-6-Hydroxy-2,5,7,8-tetramethyl-chroman-2-carboxylic acid (R)-(+)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (R)-Trolox CAS 53101-49-8

Purity 97%+In StockPharmaceutical Standards
CAS No.53101-49-8
Molecular FormulaC14H24O4
Molecular Weight256.34 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1O8B70QB9P 53101-49-8 6-Hydroxy-2,5,7,8-tetramethyl-chroman-2-carboxylic acid, (+)- UNII-1O8B70QB9P 2H-1-Benzopyran-2-carboxylic acid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-, (2R)- 2H-1-Benzopyran-2-carboxylic acid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-, (R)- (+)-6-Hydroxy-2,5,7,8-tetramethyl-chroman-2-carboxylic acid (R)-(+)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (R)-Trolox CAS 53101-49-8 chemical structure

Description

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

1O8B70QB9P 53101-49-8 6-Hydroxy-2,5,7,8-tetramethyl-chroman-2-carboxylic acid, (+)- UNII-1O8B70QB9P 2H-1-Benzopyran-2-carboxylic acid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-, (2R)- 2H-1-Benzopyran-2-carboxylic acid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-, (R)- (+)-6-Hydroxy-2,5,7,8-tetramethyl-chroman-2-carboxylic acid (R)-(+)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (R)-Trolox (CAS 53101-49-8), molecular formula C14H24O4 and molecular weight 256.34 g/mol, is a CATO reference standard with documented purity and traceability.

1O8B70QB9P 53101-49-8 6-Hydroxy-2,5,7,8-tetramethyl-chroman-2-carboxylic acid, (+)- UNII-1O8B70QB9P 2H-1-Benzopyran-2-carboxylic acid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-, (2R)- 2H-1-Benzopyran-2-carboxylic acid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-, (R)- (+)-6-Hydroxy-2,5,7,8-tetramethyl-chroman-2-carboxylic acid (R)-(+)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (R)-Trolox (C14H24O4) contains a carboxylic acid group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC14H24O4
Molecular Weight256.34 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1972

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