2-Chloro-6-methylpyridin-4-ol CAS 42779-75-9
| CAS No. | 42779-75-9 |
| Molecular Formula | C6H6ClNO |
| Molecular Weight | 143.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-Chloro-6-methylpyridin-4-ol (CAS 42779-75-9), molecular formula C6H6ClNO and molecular weight 143.57 g/mol, is a CATO reference standard with documented purity and traceability.
2-Chloro-6-methylpyridin-4-ol (C6H6ClNO) contains an amide group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H6ClNO |
| Molecular Weight | 143.57 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1969 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 5-Chloro-6-methylpyridin-2-ol (CAS 103997-23-5)
- N-(3-Chloro-phenyl)hydroxylamine (CAS 10468-17-4)
- (5-Chloro pyrazin-2-yl) Methanamine (CAS 1060814-53-0)
- 4-Chloro-3-methylpyridine 1-Oxide (CAS 1073-34-3)
- 2-Chloro-3-hydrazinylpyridine (CAS 117087-45-3)
- 5-Chloro-2-methylpyridin-4(1H)-one (CAS 1196157-19-3)
- 2-Chloro-1-(1H-pyrrol-3-yl)ethanone (CAS 122450-28-6)
- 3-Chloro-2-methylpyridin-4-ol (CAS 1227499-23-1)
Recommended Standards
- 2-Chloro-6-methylpyridin-3-ol (CAS 35680-24-1)
- 2-Chloro-6-methylpyridine 1-oxide (CAS 52313-59-4)
- 2-Chloro-6-hydrazinopyridine (CAS 5193-03-3)
- 2-Chloro-N-methylpyrimidin-4-amine (CAS 66131-68-8)
- tert-Butyl (2-(trifluoromethyl)piperidin-3-yl)carbamate (CAS 1824347-45-6)
- 6-Chloro-3-nitroquinolin-4-ol (CAS 101861-61-4)
- Ethyl 5-bromo-3-cyano-2-methoxybenzoate (CAS 1807208-96-3)
- Benzyl 3,5-dimethylpiperazine-1-carboxylate hydrochloride (CAS 1803600-54-5)
- (2S,3R)-3-(2-ethoxyphenoxy)-2-hydroxy-3-phenylpropyl 4-nitrobenzoate (CAS 98769-70-1)
- 2-Boc-6-chloro-3,4-dihydro-1H-isoquinoline-1-carboxylic acid (CAS 871730-33-5)
- 2-((Ethylamino)methyl)phenol (CAS 108206-05-9)
- 1,4,4-Trifluorocyclohexane-1-carboxylic acid (CAS 1645565-22-5)
- (4-bromothiophen-2-yl)boronic acid (CAS 499769-92-5)
- Peptide YY (canine, mouse, porcine, rat) trifluoroacetate salt (CAS 81858-94-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com