5-(1,3-Dioxolan-2-yl)-2-fluorobenzofuran CAS 648449-73-4
| CAS No. | 648449-73-4 |
| Molecular Formula | C11H9FO3 |
| Molecular Weight | 208.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 5-(1,3-Dioxolan-2-yl)-2-fluorobenzofuran (CAS 648449-73-4), a certified reference material (molecular formula C11H9FO3, MW 208.19 g/mol) for analytical method development and quality control.
5-(1,3-Dioxolan-2-yl)-2-fluorobenzofuran (C11H9FO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-(1,3-Dioxolan-2-yl)-2-fluorobenzofuran under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H9FO3 |
| Molecular Weight | 208.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
Related Dioxolan Standards
- 6-(1,3-Dioxolan-2-yl)-2-fluorobenzofuran (CAS 648915-97-3)
- (Z)-4-(1,3-Dioxolan-2-yl)-N'-hydroxybenzimidamide (CAS 1236148-81-4)
- Methyl 3-(1,3-dioxolan-2-yl)benzoate (CAS 124038-36-4)
- 2-((1,3-Dioxolan-2-yl)methoxy)benzaldehyde (CAS 23145-22-4)
- 2-(1,3-Dioxolan-2-ylmethyl)benzoic acid (CAS 898767-07-2)
- 3-((1,3-Dioxolan-2-yl)methoxy)benzaldehyde (CAS 850348-84-4)
- 3-(1,3-Dioxolan-2-ylmethyl)benzoic acid (CAS 898767-05-0)
- 4-((1,3-Dioxolan-2-yl)methyl)benzoic acid (CAS 898767-03-8)
Recommended Standards
- 4-Nitrobenzoyl Isothiocyanate (CAS 28115-92-6)
- 5-(4-Fluorophenyl)-5-methylimidazolidine-2,4-dione (CAS 428-22-8)
- 4-ethyl-3-fluoro-7-hydroxy-chromen-2-one (CAS 2920243-34-9)
- 5-Fluoro-2-benzofurancarboxylic Acid Ethyl Ester (CAS 93849-31-1)
- 1,5-Dimethoxy-2-methyl-3-nitrobenzene (CAS 16024-31-0)
- 1,2,4,7,9-Pentachlorodibenzo[b,d]furan (CAS 71998-74-8)
- C.I. Acid Orange 6 (Free Acid) (CAS 2050-34-2)
- 3-((4-Methyl-2-nitrophenoxy)methyl)benzohydrazide (CAS 832737-80-1)
- 5H-Octafluoropentanoic Acid (CAS 376-72-7)
- Clopidogrel Impurity 130 (CAS CATO-C4X-1029130)
- (5-methylpyridin-2-yl)methyl acetate (CAS 772-71-4)
- 2373-51-5 Chlorodimethyl sulfide Chloromethyl methyl sulphide Methane, chloro(methylthio)- (9CI) Sulfide, chloromethyl methyl 4-01-00-03079 (Beilstein Handbook Reference) AI3-61511 BRN 1730851 CCRIS 7530 Chlorodimethyl thioether Chloromethyl methyl sulfide Chloromethyl methyl thioether Chloro(methylthio)methane Clorodimetilsolfuro [Italian] EINECS 219-148-4 Methylthiomethyl chloride Monochlorodimethyl sulfide NSC 63205 Clorodimetilsolfuro (CAS 2373-51-5)
- (6-(Indolin-1-yl)pyridin-3-yl)(phenyl)methanol (CAS 1355219-50-9)
- Cyclopeptide-5 (CAS 197172-76-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com