2,4,5-Trimethoxybenzoyl chloride CAS 42833-66-9
| CAS No. | 42833-66-9 |
| Molecular Formula | C10H11ClO4 |
| Molecular Weight | 230.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,4,5-Trimethoxybenzoyl chloride (CAS 42833-66-9) is a high-purity analytical reference standard with the molecular formula C10H11ClO4 and a molecular weight of 230.64 g/mol.
The molecular framework of 2,4,5-Trimethoxybenzoyl chloride (C10H11ClO4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2,4,5-Trimethoxybenzoyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H11ClO4 |
| Molecular Weight | 230.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1969 |
| Halogen Content | Cl-containing |
Related Trimethoxybenzoyl Standards
- 2,4,6-Trimethoxybenzoyl chloride (CAS 42833-84-1)
- 3,4,5-Trimethoxybenzoyl isothiocyanate (CAS 6939-63-5)
- 1-(2,4,5-Trimethoxybenzoyl)-1H-imidazole (CAS 1424857-13-5)
- 1-(3,4,5-Trimethoxybenzoyl)piperazine (CAS 53342-13-5)
- (2S)-2-[(3,4,5-Trimethoxybenzoyl)-amino]propanoic acid (CAS 93709-67-2)
- 3-Methyl-1-(3,4,5-trimethoxybenzoyl)piperazine (CAS 1240564-32-2)
- 2-Methyl-1-(3,4,5-trimethoxybenzoyl)piperazine (CAS 1240565-33-6)
- 1-(3,4,5-Trimethoxybenzoyl)-1,4-diazepane (CAS 99822-56-7)
Recommended Standards
- 2-(Chloromethyl)-5-((tetrahydrofuran-2-yl)oxy)-4H-pyran-4-one (CAS 90376-16-2)
- 2-(5-Chloro-2,4-dimethoxyphenyl)acetic acid (CAS 383133-88-8)
- 2-chloro-1-(2-hydroxy-3,4-dimethoxyphenyl)ethanone (CAS 7507-92-8)
- 2-(4-Chloro-5-methoxy-2-methylphenoxy)acetic acid (CAS 2758-49-8)
- 4-(5-Methoxy-2-methyl-1H-indol-3-yl)-2-thiazolamine (CAS 50825-20-2)
- Naphthalen-2-yl (1R,4R,7R)-7-isopropyl-5-methylbicyclo[2.2.2]octa-2,5-diene-2-carboxylate (CAS 1188966-75-7)
- 2,4-Difluoro-3-methoxybenzenesulfonyl chloride (CAS 1706458-65-2)
- Glutathione Impurity 27 (CAS CATO-C4X-118527)
- 3-[3-(difluoromethoxy)phenyl]-1h-pyrazole-4-carboxylic acid (CAS 1152974-89-4)
- n-(4-Fluoro-3-methylbenzyl)-2-methylpropan-1-amine (CAS 1249303-29-4)
- Lercanidipine Impurity 28 (CAS 2250242-51-2)
- 3-(4-Chloro-3-nitrophenyl)-2-(phenylcarbonyl)prop-2-enenitrile (CAS 1025318-05-1)
- 7-((4-Methylthiazol-2-yl)thio)heptanoic acid (CAS 40107-51-5)
- Semaglutide Impurity 9 (CAS CATO-C4X-22269)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com