2-(Chloromethyl)-5-((tetrahydrofuran-2-yl)oxy)-4H-pyran-4-one CAS 90376-16-2
| CAS No. | 90376-16-2 |
| Molecular Formula | C10H11ClO4 |
| Molecular Weight | 230.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(Chloromethyl)-5-((tetrahydrofuran-2-yl)oxy)-4H-pyran-4-one.
2-(Chloromethyl)-5-((tetrahydrofuran-2-yl)oxy)-4H-pyran-4-one (CAS 90376-16-2), molecular formula C10H11ClO4 and molecular weight 230.64 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-(Chloromethyl)-5-((tetrahydrofuran-2-yl)oxy)-4H-pyran-4-one (C10H11ClO4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 230.64 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H11ClO4 |
| Molecular Weight | 230.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | Cl-containing |
Related Chloromethyl Standards
- 2-(Chloromethyl)-3-(difluoromethyl)-5-methylpyridine-4-acetonitrile (CAS 1361499-86-6)
- 2-(Chloromethyl)-6-(difluoromethyl)-4-methylpyridine-3-acetonitrile (CAS 1361695-34-2)
- 2-(Chloromethyl)-3-(difluoromethyl)-4-methylpyridine-5-acetonitrile (CAS 1361699-35-5)
- 2-(Chloromethyl)-5-(difluoromethyl)-3-methylpyridine-4-acetonitrile (CAS 1361751-86-1)
- 2-(Chloromethyl)-6-(difluoromethyl)-5-methylpyridine-3-acetonitrile (CAS 1361751-92-9)
- 2-(Chloromethyl)-4-(difluoromethyl)-3-methylpyridine-6-acetonitrile (CAS 1361800-32-9)
- 2-(Chloromethyl)-5-(difluoromethyl)-6-methylpyridine-3-acetonitrile (CAS 1361800-43-2)
- 2-(Chloromethyl)-5-(difluoromethyl)-4-methylpyridine-3-acetonitrile (CAS 1361808-71-0)
Recommended Standards
- 2-(5-Chloro-2,4-dimethoxyphenyl)acetic acid (CAS 383133-88-8)
- 2,4,5-Trimethoxybenzoyl chloride (CAS 42833-66-9)
- 2-(4-Chloro-5-methoxy-2-methylphenoxy)acetic acid (CAS 2758-49-8)
- 2,4,6-Trimethoxybenzoyl chloride (CAS 42833-84-1)
- Ethyl 4-((3-amino-2-oxo-2H-chromen-4-yl)amino)benzoate (CAS 313231-50-4)
- (3R,4R)-4-(dimethylamino)pyrrolidin-3-ol (CAS 1033718-81-8)
- 4-Methoxy-N-(3-methoxypropyl)-4-methylpentan-2-amine (CAS 1152597-51-7)
- Methyl 1-isopropyl-6-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1245808-34-7)
- 3-[4-(trifluoromethyl)-1,3-thiazol-2-yl]piperidine (CAS 1249566-89-9)
- 4-Cyclopropyl-1-(2,4-dimethylphenyl)-1,6-dihydro-7H-pyrazolo[3,4-d]pyridazin-7-one (CAS 1105197-25-8)
- 2-Methoxy-N-methylbenzamide (CAS 3400-35-9)
- 1-ethyl-6-oxo-1,4,5,6-tetrahydropyridazine-3-carboxylic acid (CAS 171672-94-9)
- 4,4'-Oxybis(benzene-1,2-diamine) (CAS 2676-59-7)
- Insulin Degludec Impurity 2 (CAS CATO-C4X-21572)
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