4-((2-Fluorobenzyl)oxy)-3-iodo-5-methoxybenzaldehyde CAS 428847-21-6
| CAS No. | 428847-21-6 |
| Molecular Formula | C15H12FIO3 |
| Molecular Weight | 386.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 386.16 g/mol gives 4-((2-Fluorobenzyl)oxy)-3-iodo-5-methoxybenzaldehyde distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 4-((2-Fluorobenzyl)oxy)-3-iodo-5-methoxybenzaldehyde (CAS 428847-21-6), a certified reference material (molecular formula C15H12FIO3, MW 386.16 g/mol) for analytical method development and quality control.
The molecular framework of 4-((2-Fluorobenzyl)oxy)-3-iodo-5-methoxybenzaldehyde (C15H12FIO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/iodine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-((2-Fluorobenzyl)oxy)-3-iodo-5-methoxybenzaldehyde under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H12FIO3 |
| Molecular Weight | 386.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/I-containing |
Related Fluorobenzyl Standards
- 4-((4-Fluorobenzyl)oxy)-3-iodobenzohydrazide (CAS 1706438-94-9)
- 4-((3-Fluorobenzyl)oxy)-3-iodobenzohydrazide (CAS 1706458-42-5)
- (3-(2-((4-Fluorobenzyl)oxy)phenyl)-1H-pyrazol-1-yl)(p-tolyl)methanone (CAS 477713-46-5)
- 2-((3-(4-Fluorobenzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)thio)-1-(piperidin-1-yl)ethan-1-one (CAS 863453-08-1)
- 4-(2-(1-(4-Fluorobenzyl)-1H-indol-3-yl)ethyl)thiomorpholine 1,1-dioxide (CAS 478040-87-8)
- 5-((2-Fluorobenzyl)thio)-8,9-dimethoxyimidazo[1,2-c]quinazolin-2(3H)-one (CAS 439109-27-0)
- 5-((3-Fluorobenzyl)thio)-8,9-dimethoxyimidazo[1,2-c]quinazolin-2(3H)-one (CAS 672949-23-4)
- 5-((4-Fluorobenzyl)thio)-8,9-dimethoxyimidazo[1,2-c]quinazolin-2(3H)-one (CAS 439109-12-3)
Recommended Standards
- 2,2,3,4,4,4-Hexafluorobutyl (4,4,5,5,5-pentafluoropentyl) carbonate (CAS 1980086-68-7)
- 5-(2,4-Dichlorophenoxy)-3-phenyl-6-(trifluoromethyl)-1,2,4-triazine (CAS 672950-86-6)
- (2E)-3-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-(4-chlorophenyl)-2-cyanoprop-2-enamide (CAS 338978-46-4)
- Isopropyl (2,2,3,3,4,4,5,5,6,6,6-undecafluorohexyl) carbonate (CAS 1980085-46-8)
- (S)-4-Methoxybutan-2-amine hydrochloride (CAS 1380094-24-5)
- Methyl 4-(2-oxo-1,3-oxazinan-3-yl)benzoate (CAS 1031927-08-8)
- Methyl 2-(4-Aminotetrahydropyran-4-yl)acetate (CAS 178242-93-8)
- (R)-N-(1-(4-cyanophenyl)ethyl)acetamide (CAS 199442-00-7)
- 1-Chlorovinyl-Benzene (CAS 618-34-8)
- 2,5-Dimethyl-1-(pyridin-2-ylmethyl)-1h-pyrrole-3-carboxylic acid (CAS 953717-09-4)
- (3AR,4S,6R,6aS)-6-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxole-4-carbaldehyde (CAS 1379540-71-2)
- 3-Methyl-2-(thiophen-2-yl)quinoline-4-carboxylic acid (CAS 204847-10-9)
- 7-AVCA Impurity 2 (CAS 33748-00-4)
- Tirzepatide Impurity 18 (CAS CATO-C4X-324018)
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