UMD07X179E 428863-50-7 Certolizumab Pegol Certolizumab pegol [USAN:INN:BAN:JAN] Immunoglobulin, anti-(human tumor necrosis factor alpha) Fab' fragment (human-mouse monoclonal CDP870 heavy chain), disulfide with human-mouse monoclonal CDP870 light chain, pegylated Immunoglobulin, anti-(human tumor necrosis factor alpha) Fab' fragment (human-mouse monoclonal CDP870 heavy chain), disulfide with human-mouse monoclonal CDP870 light chain, pegylated. Molecular weight is 47,696 daltons (unpegylated moiety) CDP 870 PHA 738144 PHA-738144 Cimzia UNII-UMD07X179E CDP870 CZP Certolizumab HSDB 7848 CAS 428863-50-7
| CAS No. | 428863-50-7 |
| Molecular Formula | C24H22F3N |
| Molecular Weight | 381.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including UMD07X179E 428863-50-7 Certolizumab Pegol Certolizumab pegol [USAN:INN:BAN:JAN] Immunoglobulin, anti-(human tumor necrosis factor alpha) Fab' fragment (human-mouse monoclonal CDP870 heavy chain), disulfide with human-mouse monoclonal CDP870 light chain, pegylated Immunoglobulin, anti-(human tumor necrosis factor alpha) Fab' fragment (human-mouse monoclonal CDP870 heavy chain), disulfide with human-mouse monoclonal CDP870 light chain, pegylated. Molecular weight is 47,696 daltons (unpegylated moiety) CDP 870 PHA 738144 PHA-738144 Cimzia UNII-UMD07X179E CDP870 CZP Certolizumab HSDB 7848.
UMD07X179E 428863-50-7 Certolizumab Pegol Certolizumab pegol [USAN:INN:BAN:JAN] Immunoglobulin, anti-(human tumor necrosis factor alpha) Fab' fragment (human-mouse monoclonal CDP870 heavy chain), disulfide with human-mouse monoclonal CDP870 light chain, pegylated Immunoglobulin, anti-(human tumor necrosis factor alpha) Fab' fragment (human-mouse monoclonal CDP870 heavy chain), disulfide with human-mouse monoclonal CDP870 light chain, pegylated. Molecular weight is 47,696 daltons (unpegylated moiety) CDP 870 PHA 738144 PHA-738144 Cimzia UNII-UMD07X179E CDP870 CZP Certolizumab HSDB 7848 (CAS 428863-50-7) is a high-purity analytical reference standard with the molecular formula C24H22F3N and a molecular weight of 381.43 g/mol.
UMD07X179E 428863-50-7 Certolizumab Pegol Certolizumab pegol [USAN:INN:BAN:JAN] Immunoglobulin, anti-(human tumor necrosis factor alpha) Fab' fragment (human-mouse monoclonal CDP870 heavy chain), disulfide with human-mouse monoclonal CDP870 light chain, pegylated Immunoglobulin, anti-(human tumor necrosis factor alpha) Fab' fragment (human-mouse monoclonal CDP870 heavy chain), disulfide with human-mouse monoclonal CDP870 light chain, pegylated. Molecular weight is 47,696 daltons (unpegylated moiety) CDP 870 PHA 738144 PHA-738144 Cimzia UNII-UMD07X179E CDP870 CZP Certolizumab HSDB 7848 (C24H22F3N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H22F3N |
| Molecular Weight | 381.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
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- (2E)-N-(Butan-2-yl)-3-{4-[(2,4-dichlorophenyl)methoxy]phenyl}prop-2-enamide (CAS 477888-87-2)
- 2,5-Di(thiophen-2-yl)furan (CAS 88089-34-3)
- N-(Imino(1H-pyrazol-1-yl)methyl)-2,2-dimethylhexanamide (CAS 185252-51-1)
- Semaglutide impurity 29 (CAS CATO-C4X-222629)
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