6-Amino-3,4-dihydro-2h-1,3-benzoxazine-2,4-dione CAS 4297-75-0
| CAS No. | 4297-75-0 |
| Molecular Formula | C8H7F7O4S |
| Molecular Weight | 332.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
6-Amino-3,4-dihydro-2h-1,3-benzoxazine-2,4-dione (CAS 4297-75-0), molecular formula C8H7F7O4S and molecular weight 332.19 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 6-Amino-3,4-dihydro-2h-1,3-benzoxazine-2,4-dione (C8H7F7O4S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H7F7O4S |
| Molecular Weight | 332.19 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
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