2,4-Dichloro-6-(chloromethyl)-5-methylpyrimidine CAS 430440-91-8
| CAS No. | 430440-91-8 |
| Molecular Formula | C6H5Cl3N2 |
| Molecular Weight | 211.48 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 2,4-Dichloro-6-(chloromethyl)-5-methylpyrimidine (CAS 430440-91-8), a certified reference material (molecular formula C6H5Cl3N2, MW 211.48 g/mol) for analytical method development and quality control.
2,4-Dichloro-6-(chloromethyl)-5-methylpyrimidine (C6H5Cl3N2) contains a nitrile group, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 2,4-Dichloro-6-(chloromethyl)-5-methylpyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H5Cl3N2 |
| Molecular Weight | 211.48 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichloro Standards
- 2,4-Dichloro-5-(chloromethyl)-6-methylpyrimidine (CAS 16768-43-7)
- 1,2-Dichloro-4-(dichloromethoxy)benzene (CAS 94637-84-0)
- 2,6-Dichloro-2,6-dimethyl-heptan-4-one (CAS 66886-69-9)
- 2,4-Dichloro-5-methylfuro[2,3-d]pyrimidine (CAS 1160994-79-5)
- 4,6-dichloro-3-methyl-1h-pyrazolo[3,4-d]pyrimidine (CAS 1211522-68-7)
- 5,7-dichloro-2-methyl-2H-pyrazolo[4,3-d]pyrimidine (CAS 1357087-30-9)
- 4,6-dichloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine (CAS 98141-42-5)
- 4,6-dichloro-2-methyl-2H-pyrazolo[3,4-d]pyrimidine (CAS 959432-77-0)
Recommended Standards
- 2,4,6-Trichlorophenylhydrazine (CAS 5329-12-4)
- 3,4,5-Trichlorobenzene-1,2-diamine (CAS 30064-28-9)
- 2,4,6-Trichlorobenzene-1,3-diamine (CAS 3102-85-0)
- Abemaciclib impurity 117 (CAS CATO-C4X-2937117)
- 4-Hydroxy-2,2-dimethyl-2,3-dihydrobenzofuran-6-carboxylic acid (CAS 169130-42-1)
- N-(4-Methylpyridin-2-yl)-6-(piperazin-1-yl)pyridazin-3-amine (CAS 1706446-74-3)
- Tert-butyl (3-((thietan-3-ylamino)methyl)pentan-3-yl)carbamate (CAS 1994239-98-3)
- 1-amino-1-(2-methyl-1,3-thiazol-4-yl)propan-2-ol dihydrochloride (CAS 1909319-96-5)
- N-((1-(Pyrazin-2-yl)piperidin-4-yl)methyl)benzofuran-2-carboxamide (CAS 1396877-21-6)
- 5-Amino-2-fluorobenzyl bromide (CAS 518057-73-3)
- N',2-bis(3,4-dimethylphenyl)hydrazine-1-carbohydrazide (CAS 29674-79-1)
- 1,2-Bis(4-(octyloxy)phenyl)ethane-1,2-dione (CAS 35763-07-6)
- 3-(Benzyloxy)-2-methylphenol (CAS 79572-20-6)
- Acetyl Tripeptide-1 (CAS 350595-76-5)
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