4-(1H-Indol-3-yl)-5-methyl-thiazol-2-ylamine CAS 430442-17-4
| CAS No. | 430442-17-4 |
| Molecular Formula | C12H11N3S |
| Molecular Weight | 229.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-(1H-Indol-3-yl)-5-methyl-thiazol-2-ylamine (C12H11N3S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
4-(1H-Indol-3-yl)-5-methyl-thiazol-2-ylamine (CAS 430442-17-4) is a high-purity analytical reference standard with the molecular formula C12H11N3S and a molecular weight of 229.30 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(1H-Indol-3-yl)-5-methyl-thiazol-2-ylamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H11N3S |
| Molecular Weight | 229.30 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related H Standards
- 1-((1H-Indol-3-yl)methyl)piperidin-4-amine (CAS 72807-18-2)
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