1-(4-(2-Chloro-6-nitrophenyl)piperazin-1-yl)ethan-1-one CAS 430451-25-5
| CAS No. | 430451-25-5 |
| Molecular Formula | C12H14ClN3O3 |
| Molecular Weight | 283.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(4-(2-Chloro-6-nitrophenyl)piperazin-1-yl)ethan-1-one.
1-(4-(2-Chloro-6-nitrophenyl)piperazin-1-yl)ethan-1-one (CAS 430451-25-5), molecular formula C12H14ClN3O3 and molecular weight 283.71 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 1-(4-(2-Chloro-6-nitrophenyl)piperazin-1-yl)ethan-1-one (C12H14ClN3O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 283.71 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(4-(2-Chloro-6-nitrophenyl)piperazin-1-yl)ethan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H14ClN3O3 |
| Molecular Weight | 283.71 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 2-Chloro-1-[4-(2-nitrophenyl)piperazin-1-yl]ethan-1-one (CAS 1000930-18-6)
- 1-(4-(2-Chloro-4-nitrophenyl)piperazin-1-yl)ethan-1-one (CAS 101970-40-5)
- 3-(6-Chloro-2,2-dimethyl-3-oxo-2,3-dihydro-4H-benzo[b][1,4]oxazin-4-yl)propanoic acid (CAS 1082570-52-2)
- 2-Chloro-3-(phenylamino)naphthalene-1,4-dione (CAS 1090-16-0)
- (5-Chloro-2-methoxybenzoyl)proline (CAS 1101860-80-3)
- 1-(2-Chloro-5-nitrobenzoyl)-1,4-diazepane (CAS 1156199-38-0)
- 1-(4-Chloro-3-nitrobenzoyl)-3-methylpiperazine (CAS 1240564-68-4)
- 1-(4-Chloro-3-nitrobenzoyl)-1,4-diazepane (CAS 1240573-70-9)
Recommended Standards
- 1-(3-Chlorophenyl)isoquinoline-3-carboxylic acid (CAS 89242-14-8)
- 1-(4-(4-Chloro-2-nitrophenyl)piperazin-1-yl)ethan-1-one (CAS 329922-78-3)
- 1-(3-Chlorophenyl)-3-(pyridin-3-yl)-1H-pyrazole-4-carbaldehyde (CAS 618101-73-8)
- 1-(4-Chlorobenzoyl)-1H-indole-3-carbaldehyde (CAS 62189-77-9)
- 1-Ethyl-4-(2-(4-nitrophenyl)hydrazono)piperidine (CAS 380493-82-3)
- Tert-butyl6-amino-2-azaspiro[3.5]nonane-2-carboxylate (CAS 2168997-21-3)
- Ethyl 3-methyl-5,6-diphenylpyridazine-4-carboxylate (CAS 62139-82-6)
- 2-((4-Allyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(2,6-dimethylphenyl)acetamide (CAS 578754-93-5)
- 3-Bromo-2-chloro-5-fluorobenzotrifluoride (CAS 1027511-98-3)
- (4-Chlorophenyl)(cyclopropyl)methanone (CAS 6640-25-1)
- Venlafaxine EP Impurity G HCl (CAS 2108968-20-1)
- 4-fluoro-3-methanesulfonylbenzene-1-sulfonamide (CAS 1065603-81-7)
- 1-(6-(4-Isopropylpiperazin-1-yl)-2-methylpyridin-3-yl)propan-1-one (CAS 1355223-35-6)
- Peptide Impurity 81 TFA (CAS CATO-CPTD788581)
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