6-Hydroxyquinoline-4-carboxylic Acid CAS 4312-44-1
| CAS No. | 4312-44-1 |
| Molecular Formula | C10H7NO3 |
| Molecular Weight | 189.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Hydroxyquinoline-4-carboxylic Acid.
6-Hydroxyquinoline-4-carboxylic Acid (CAS 4312-44-1), molecular formula C10H7NO3 and molecular weight 189.17 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 6-Hydroxyquinoline-4-carboxylic Acid (C10H7NO3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-Hydroxyquinoline-4-carboxylic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H7NO3 |
| Molecular Weight | 189.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 1 |
Related Hydroxyquinoline Standards
- 7-Hydroxyquinoline-4-carboxylic acid (CAS 1017969-32-2)
- 6-Hydroxyquinoline-3-carboxylic acid (CAS 1137826-05-1)
- 7-Hydroxyquinoline-8-carboxylic acid (CAS 1146298-53-4)
- 4-Hydroxyquinoline-7-carboxylic acid (CAS 1150618-22-6)
- 3-Hydroxyquinoline-4-carboxylic acid (CAS 118-13-8)
- 7-Hydroxyquinoline-6-carboxylic acid (CAS 1227608-04-9)
- 3-Hydroxyquinoline-6-carboxylic acid (CAS 1233244-78-4)
- 6-Hydroxyquinoline-7-carboxylic acid (CAS 1261434-11-0)
Recommended Standards
- 6-Hydroxyisoquinoline-3-carboxylic acid (CAS 850305-96-3)
- 6-Hydroxyquinoline-5-carboxylic acid (CAS 27230-42-8)
- 6-Hydroxy-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile (CAS 2305070-03-3)
- 6-Hydroxyquinoline-8-carboxylic acid (CAS 70585-55-6)
- tert-Butyl (5-bromo-4-cyano-3-iodopyridin-2-yl)carbamate (CAS 2768872-53-1)
- 4-(3-Hydroxy-3-methyloctyl)hexahydro-2H-cyclopenta[b]furan-2,5-diol (CAS 62145-17-9)
- 2-Bromo-6-((4,4-difluoropiperidin-1-yl)methyl)pyridine (CAS 2024560-45-8)
- 3-chloro-4-[(3,4-difluorophenyl)methoxy]benzoic acid (CAS 1355636-71-3)
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- Tris(4-(dimethylamino)phenyl)phosphine oxide (CAS 807-20-5)
- 2,5-Bis(methylsulfonyl)benzene-1,4-diamine (CAS 1678513-97-7)
- NS-2028 (CAS 204326-43-2)
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- (Ser(PO?H?)2?2)-Tau Peptide (260-264) PAb Blocking trifluoroacetate salt (CAS 2022956-57-4)
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