1,1,1-Trifluoro-4-phenylbutan-2-one CAS 86571-26-8

Purity 97%+In StockPharmaceutical Standards
CAS No.86571-26-8
Molecular FormulaC10H9F3O
Molecular Weight202.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1,1,1-Trifluoro-4-phenylbutan-2-one CAS 86571-26-8 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 202.17 g/mol gives 1,1,1-Trifluoro-4-phenylbutan-2-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

1,1,1-Trifluoro-4-phenylbutan-2-one (CAS 86571-26-8) is a high-purity analytical reference standard with the molecular formula C10H9F3O and a molecular weight of 202.17 g/mol.

The molecular framework of 1,1,1-Trifluoro-4-phenylbutan-2-one (C10H9F3O) is characterized by a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1,1,1-Trifluoro-4-phenylbutan-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H9F3O
Molecular Weight202.17 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1981
Halogen ContentF-containing

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