n-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl}-n-phenylmethanesulfonamide CAS 431985-74-9
| CAS No. | 431985-74-9 |
| Molecular Formula | C19H22FN3O3S |
| Molecular Weight | 391.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of n-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl}-n-phenylmethanesulfonamide (C19H22FN3O3S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
n-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl}-n-phenylmethanesulfonamide (CAS 431985-74-9) is a high-purity analytical reference standard with the molecular formula C19H22FN3O3S and a molecular weight of 391.46 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), n-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl}-n-phenylmethanesulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H22FN3O3S |
| Molecular Weight | 391.46 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- N1-(3-Hydroxypropyl)-N2-((3-(thiophen-2-ylsulfonyl)-1,3-oxazinan-2-yl)methyl)oxalamide (CAS 872986-73-7)
- Tert-butyl (3S)-3-amino-4-(trifluoromethyl)piperidine-1-carboxylate (CAS 2166381-92-4)
- 1-[(5-Aminopentyl)oxy]-4-chlorobenzene (CAS 200484-40-8)
- N-(3-Isobutoxybenzyl)-1-phenyl-1-ethanamine (CAS 1040690-57-0)
- Fexofenadine Impurity 37 (CAS CATO-C4X-179437)
- 5-Allyl-1-ethoxy-2,3-difluorobenzene (CAS 1378820-24-6)
- 6-Fluoro-2,4'-bipyridine (CAS 1214360-31-2)
- n-(1-Methylpiperidin-4-yl)-1h-indazol-6-amine (CAS 416880-15-4)
- 5,6-Bis((trimethylsilyl)ethynyl)-1,2-dihydroacenaphthylene (CAS 364038-98-2)
- 2-Bromo-4-(piperidin-1-yl)pyrimidine (CAS 1209458-77-4)
- Peptide YY (3-36) (human) (CAS 123583-37-9)
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