N-(2-aminophenyl)benzenesulfonamide CAS 43200-31-3
| CAS No. | 43200-31-3 |
| Molecular Formula | C12H12N2O2S |
| Molecular Weight | 248.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies N-(2-aminophenyl)benzenesulfonamide (CAS 43200-31-3), a certified reference material (molecular formula C12H12N2O2S, MW 248.30 g/mol) for analytical method development and quality control.
The molecular framework of N-(2-aminophenyl)benzenesulfonamide (C12H12N2O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(2-aminophenyl)benzenesulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H12N2O2S |
| Molecular Weight | 248.30 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1969 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related N Standards
- N-(3-aminophenyl)benzenesulfonamide (CAS 104997-09-3)
- 5-(2-Aminophenyl)-3-(ethylthio)-1,2,4-triazin-6-ol (CAS 1119452-05-9)
- 3-((4-aminophenyl)sulfonyl)aniline (CAS 34262-32-3)
- 6-(2-Aminophenyl)-3-(ethylthio)-1,2,4-triazin-5(4H)-one (CAS 405921-19-9)
- Ethyl 2-(4-Aminophenyl)thiazole-4-carboxylate (CAS 730234-73-8)
- Ethyl 4-(3-aminophenyl)thiazole-2-carboxylate (CAS 460750-28-1)
- Ethyl 4-(4-aminophenyl)thiazole-2-carboxylate (CAS 491577-82-3)
- N-(4-Aminophenyl)benzenesulfonamide (CAS 5466-91-1)
Recommended Standards
- Methyl n-(2-methyl-4-phenyl-1,3-thiazol-5-yl)carbamate (CAS 41260-96-2)
- N-(4-(Dimethylamino)phenyl)-1,2,5-thiadiazole-3-carboxamide (CAS 700850-84-6)
- Methyl 5-(4-methoxyphenyl)thiophene-2-carboxylate (CAS 69202-21-7)
- Methyl 2-amino-5-benzyl-1,3-thiazole-4-carboxylate (CAS 864437-28-5)
- 2-(Cyclohexylmethoxy)-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile (CAS 2490666-03-8)
- [1-(3,4-Dichlorophenyl)-1H-1,2,3-triazol-4-yl]methyl 2,4-dichlorobenzoate (CAS 338419-41-3)
- 1-(3-(Methylamino)pyrrolidin-1-yl)ethanone (CAS 863248-50-4)
- Gatifloxacin impurity 31 (CAS CATO-C4X-125331)
- 1,1-Difluoro-n-methylmethanesulfonamide (CAS 1038306-70-5)
- Famotidine Impurity 57 (CAS CATO-C4X-139257)
- 7-Iodo-3,4-dihydroquinazolin-4-one (CAS 202197-77-1)
- 4-[(4-Methylphenyl)sulfanyl]benzaldehyde (CAS 141339-95-9)
- methyl 3-(hydroxymethyl)cyclopentanecarboxylate (CAS 2105364-26-7)
- Semaglutide Impurity 129 (CAS 2490269-79-7)
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