Ethyl 4-(4-aminophenyl)thiazole-2-carboxylate CAS 491577-82-3
| CAS No. | 491577-82-3 |
| Molecular Formula | C12H12N2O2S |
| Molecular Weight | 248.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Ethyl 4-(4-aminophenyl)thiazole-2-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Ethyl 4-(4-aminophenyl)thiazole-2-carboxylate (CAS 491577-82-3), molecular formula C12H12N2O2S and molecular weight 248.30 g/mol, is a CATO reference standard with documented purity and traceability.
Ethyl 4-(4-aminophenyl)thiazole-2-carboxylate (C12H12N2O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H12N2O2S |
| Molecular Weight | 248.30 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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- N-(2-aminophenyl)benzenesulfonamide (CAS 43200-31-3)
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Recommended Standards
- Ethyl 4-amino-3-phenyl-1,2-thiazole-5-carboxylate (CAS 65237-13-0)
- Ethyl 4-(2-imino-2,3-dihydrothiazol-4-yl)benzoate (CAS 651042-69-2)
- Ethyl 4-methyl-2-(pyridin-2-yl)thiazole-5-carboxylate (CAS 383146-88-1)
- Ethyl 3-hydroxy-5-phenylthiophene-2-carboxylate (CAS 2158-86-3)
- 7-(3,5-Dibromo-1H-1,2,4-triazol-1-yl)heptanenitrile (CAS 1240572-54-6)
- (2-([6-(4-Phenylpiperazin-1-yl)pyrimidin-4-yl]oxy)ethyl)amine (CAS 1204296-34-3)
- 2-Cyano-3-(2,5-dimethoxyphenyl)-N-(2-methoxyphenyl)propanamide (CAS 1261016-16-3)
- (R)-(5-Bromo-1,2,3,4-tetrahydroisoquinolin-3-yl)methanol (CAS 1388838-68-3)
- 2-Amino-2-(4-iodophenyl)acetic acid (CAS 299167-68-3)
- 4-[(2-Aminoethyl)thio]-6-(trifluoromethyl)quinoline (CAS 1065076-15-4)
- 3-Bromo-2-methylbenzo[b]thiophene (CAS 10243-15-9)
- 2-(2-(4-Chlorophenyl)-4-oxopyrazolo[1,5-a]pyrazin-5(4H)-yl)-N-(3-methoxypropyl)acetamide (CAS 941939-21-5)
- Ethyl 2-[[cyano-(4-methoxyphenyl)methyl]-amino]acetate hydrochloride (CAS 1440535-50-1)
- Semaglutide Impurity 11 (CAS CATO-C4X-222611)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com