5-(4-Bromophenyl)-4-(furan-2-carbonyl)-3-hydroxy-1-(5-methyl-1,3,4-thiadiazol-2-yl)-1H-pyrrol-2(5H)-one CAS 432019-45-9
| CAS No. | 432019-45-9 |
| Molecular Formula | C18H12BrN3O4S |
| Molecular Weight | 446.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 446.27 g/mol gives 5-(4-Bromophenyl)-4-(furan-2-carbonyl)-3-hydroxy-1-(5-methyl-1,3,4-thiadiazol-2-yl)-1H-pyrrol-2(5H)-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-(4-Bromophenyl)-4-(furan-2-carbonyl)-3-hydroxy-1-(5-methyl-1,3,4-thiadiazol-2-yl)-1H-pyrrol-2(5H)-one (CAS 432019-45-9) is a high-purity analytical reference standard with the molecular formula C18H12BrN3O4S and a molecular weight of 446.27 g/mol.
The molecular framework of 5-(4-Bromophenyl)-4-(furan-2-carbonyl)-3-hydroxy-1-(5-methyl-1,3,4-thiadiazol-2-yl)-1H-pyrrol-2(5H)-one (C18H12BrN3O4S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H12BrN3O4S |
| Molecular Weight | 446.27 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Bromophenyl Standards
- Ethyl 1-(4-(4-bromophenyl)thiazol-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate (CAS 955976-70-2)
- 3-(4-Bromophenyl)-N-(4-methoxyphenyl)-[1,2,4]triazolo[4,3-c]quinazolin-5-amine (CAS 339026-14-1)
- 4-[({1-[(4-bromophenyl)methyl]piperidin-4-yl}carbamoyl)methoxy]benzamide (CAS 1427986-92-2)
- 2-(2-Bromophenyl)-N-(1-(3-(thiophen-3-yl)-1,2,4-oxadiazol-5-yl)cyclohexyl)acetamide (CAS 1396848-67-1)
- 2-((4-(4-Bromophenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)-N,N-diethylacetamide (CAS 477329-97-8)
- 2-((4-(4-Bromophenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N,N-diethylacetamide (CAS 477333-57-6)
- 2-((5-(2-Bromophenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(2,6-diethylphenyl)acetamide (CAS 332922-75-5)
- 4,7-Bis(4-bromophenyl)benzo[c][1,2,5]thiadiazole (CAS 287966-64-7)
Recommended Standards
- 3-Amino-N-(2,6-dichlorophenyl)-4-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide (CAS 626227-29-0)
- N-(3,4-dichlorophenyl)-3-((3-(trifluoromethyl)benzyl)oxy)thiophene-2-carboxamide (CAS 344272-98-6)
- 3-[(2,4-Dichlorophenyl)methoxy]-N-[4-(trifluoromethyl)phenyl]thiophene-2-carboxamide (CAS 339098-08-7)
- N-(4-chlorophenyl)-5-((4-chlorophenyl)thio)-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide (CAS 321533-82-8)
- 4-(4-Nitrophenyl)-6-phenyl-3-pyridazinamine (CAS 1099794-35-0)
- 2-Amino-4-chloronicotinic acid (CAS 605661-83-4)
- S-(3-hydroxyhexanoate) Coenzyme A (CAS 74875-70-0)
- 2-(3-Methoxyphenyl)spiro[3.3]heptan-2-amine (CAS 1491913-72-4)
- 3-Chloro-5-(cyclopentylamino)-1,2-thiazole-4-carbonitrile (CAS 1424533-72-1)
- (E)-5-Chloro-2-isopropyl-4-methyl-6-styrylpyrimidine (CAS 70170-00-2)
- Pyrazolo[1,5-a]pyridine-3-methanol (CAS 117782-76-0)
- Methyl 2-(benzo[b]thiophen-3-yl)-2-hydroxyacetate (CAS 1248193-68-1)
- Myristoyl coenzyme A (CAS 3130-72-1)
- Des-Gln19-Tirzepatide (CAS CATO-CPTD788954)
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