1,2-Bis(trifluoromethyl)benzene CAS 433-95-4
| CAS No. | 433-95-4 |
| Molecular Formula | C8H4F6 |
| Molecular Weight | 214.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1,2-Bis(trifluoromethyl)benzene.
1,2-Bis(trifluoromethyl)benzene (CAS 433-95-4) is a high-purity analytical reference standard with the molecular formula C8H4F6 and a molecular weight of 214.11 g/mol.
1,2-Bis(trifluoromethyl)benzene (C8H4F6) contains fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1,2-Bis(trifluoromethyl)benzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H4F6 |
| Molecular Weight | 214.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Bis Standards
- 1,3-Bis(trifluoromethyl)-benzene (CAS 402-31-3)
- 8-(Trifluoromethyl)imidazo[1,2-a]pyridine-2-carbaldehyde (CAS 1020040-56-5)
- 2-(trifluoromethyl)imidazo[1,2-a]pyridine-8-carbaldehyde (CAS 1033434-50-2)
- 2-(Trifluoromethyl)-1H-benzo[d]imidazole-6-carbaldehyde (CAS 106429-45-2)
- 5-(Trifluoromethyl)-2H-indazole-7-carbaldehyde (CAS 1100212-67-6)
- 4-(Trifluoromethyl)-5-azaindole-3-carboxaldehyde (CAS 1190309-96-6)
- 6-(Trifluoromethyl)-1h-pyrrolo[3,2-b]pyridine-3-carbaldehyde (CAS 1190311-65-9)
- 6-(Trifluoromethyl)-1H-pyrrolo[3,2-c]pyridine-3-carbaldehyde (CAS 1190315-73-1)
Recommended Standards
- 1,2,5-Trifluoro-4-methyl-3-trifluoromethyl-benzene (CAS 933674-92-1)
- 1,3,4-Trifluoro-2-methyl-5-trifluoromethyl-benzene (CAS 933674-91-0)
- (3R,4S,5R)-3,4-Dihydroxy-5-methyltetrahydrofuran-2-yl dihydrogen phosphate (CAS 86708-78-3)
- 1-Bromonaphthalene-D7 (CAS 37621-57-1)
- (S)-3-((tert-butoxycarbonyl)amino)-2-(2,4,5-trimethoxybenzyl)propanoic acid (CAS 1260611-03-7)
- (3AS,4R,5R,7aS)-7-bromo-2,2-dimethyl-3a,4,5,7a-tetrahydrobenzo[d][1,3]dioxole-4,5-diol (CAS 130669-72-6)
- 6-Fluorobenzisoxazol-3(2H)-one (CAS 99822-24-9)
- 4-Methyl-5-trifluoromethyl-2H-pyridazin-3-one (CAS 244268-36-8)
- 2-((2R,4AS)-4a,8-dimethyl-1,2,3,4,4a,5,6,7-octahydronaphthalen-2-yl)propan-2-ol (CAS 15051-81-7)
- 1-Chloro-2,3-difluoro-4-methylbenzene (CAS 1261737-51-2)
- cis-Zearalenone (CAS 36455-70-6)
- 2-(4-Methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetonitrile (CAS 1448871-64-4)
- 2-Amino-3-(3-(trifluoromethyl)phenyl)propan-1-ol hydrochloride (CAS 21176-61-4)
- ([D2]Gly4)-Cholecystokinin Octapeptide (sulfated) ammonium salt (CAS 1926163-74-7)
Why CATO?
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