7-Chlorobenzo[d]isothiazol-3(2H)-one CAS 4337-44-4
| CAS No. | 4337-44-4 |
| Molecular Formula | C7H4ClNOS |
| Molecular Weight | 185.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C7H4ClNOS, 7-Chlorobenzo[d]isothiazol-3(2H)-one contains an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 185.63 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
7-Chlorobenzo[d]isothiazol-3(2H)-one (CAS 4337-44-4) is a high-purity analytical reference standard with the molecular formula C7H4ClNOS and a molecular weight of 185.63 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 7-Chlorobenzo[d]isothiazol-3(2H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H4ClNOS |
| Molecular Weight | 185.63 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chlorobenzo Standards
- 5-Chlorobenzo[d][1,2,3]thiadiazol-4-amine (CAS 115398-34-0)
- 2-Chlorobenzo[d]thiazol-5-ol (CAS 1261737-67-0)
- 2-Chlorobenzo[d]oxazole-6-thiol (CAS 1803803-35-1)
- 2-Chlorobenzo[d]oxazole-4-thiol (CAS 1803863-84-4)
- 2-Chlorobenzo[d]oxazole-7-thiol (CAS 1804145-90-1)
- 2-Chlorobenzo[d]oxazole-5-thiol (CAS 1806392-03-9)
- 4-Chlorobenzo[c][1,2,5]thiadiazol-5-amine (CAS 30536-36-8)
- 4-Chlorobenzo[d]thiazol-2(3H)-one (CAS 39205-62-4)
Recommended Standards
- 6-Chlorobenzoxazole-2(3H)-thione (CAS 22876-20-6)
- 7-Chlorobenzo[d]thiazol-2(3H)-one (CAS 80416-76-8)
- 6-Chlorobenzo[d]thiazol-2(3H)-one (CAS 62266-81-3)
- 7-Chlorobenzoxazole-2(3H)-thione (CAS 51793-93-2)
- 3-(4-chlorophenyl)-3-methyloxolane-2,5-dione (CAS 1094333-80-8)
- (R)-2-Amino-1-(3-(dimethylamino)pyrrolidin-1-yl)ethanone (CAS 1354010-68-6)
- n1,n1-Dimethyl-n4-(3-methylbutan-2-yl)benzene-1,4-diamine (CAS 1156371-22-0)
- 3-Amino-N-(4-chloro-3-(trifluoromethyl)phenyl)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide (CAS 496019-30-8)
- Boc-NH-PEG5-propargyl (CAS 2062663-67-4)
- (2R)-5-Methoxy-1,3-oxathiolane-2-methanol (CAS 528567-32-0)
- N-(tert-butyl)-4-(2-fluorophenyl)piperazine-1-carboxamide (CAS 1022116-38-6)
- 4-Isobutoxyphenol (CAS 56069-36-4)
- Mometasone Furoate Impurity 11 (CAS CATO-C4X-170411)
- Insulin Degludec Impurity 17 (CAS CATO-C4X-215717)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com