3-Amino-N-(4-chloro-3-(trifluoromethyl)phenyl)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide CAS 496019-30-8
| CAS No. | 496019-30-8 |
| Molecular Formula | C20H12ClF3N4OS |
| Molecular Weight | 448.85 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
3-Amino-N-(4-chloro-3-(trifluoromethyl)phenyl)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide (CAS 496019-30-8), molecular formula C20H12ClF3N4OS and molecular weight 448.85 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 3-Amino-N-(4-chloro-3-(trifluoromethyl)phenyl)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide (C20H12ClF3N4OS) contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 448.85 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H12ClF3N4OS |
| Molecular Weight | 448.85 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Amino Standards
- Methyl 2-amino-2-oxoacetate (CAS 62155-27-5)
- 1-(23-Amino-3,6,9,12,15,18,21-heptaoxatricosyl)-1H-pyrrole-2,5-dione (CAS 1629740-94-8)
- Methyl 6-amino-5-cyano-2-{[(3-cyano-6-methylpyridin-2-yl)sulfanyl]methyl}-4-(4-methoxyphenyl)-4H-pyran-3-carboxylate (CAS 489416-89-9)
- 6-Amino-N-(4-methyl-1,3-benzothiazol-2-yl)-8-(trifluoromethyl)-4-thia-2-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,5,7-tetraene-5-carboxamide (CAS 674805-32-4)
- 2-(4-Amino-2-butoxypyridin-3-yl)-4-bromo-N,N-diisopropylbenzamide (CAS 1058129-83-1)
- 3-Amino-N-(4-bromo-2-fluorophenyl)-6-ethyl-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide (CAS 625370-21-0)
- Ethyl 2-amino-4-(2,4-dichlorophenyl)-5-oxo-4H,5H-thiochromeno[4,3-b]pyran-3-carboxylate (CAS 923551-49-9)
- Ethyl 2-amino-4-(2,6-dichlorophenyl)-5-oxo-4H,5H-thiochromeno[4,3-b]pyran-3-carboxylate (CAS 939889-03-9)
Recommended Standards
- 3-(((4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)imino)methyl)benzo[c]thiophen-1-ol (CAS 338954-42-0)
- 1,5-Bis(2-(bicyclo[2.2.1]hept-5-en-2-yl)ethyl)-1,1,3,3,5,5-hexamethyltrisiloxane (CAS 307496-39-5)
- 2-((2-Chloro-6-fluorobenzyl)thio)-5-(1-methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazol-5-yl)-1,3,4-oxadiazole (CAS 339103-41-2)
- 1-(4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-2,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indol-4-one (CAS 1023498-80-7)
- Benzyl (1-((S)-2-amino-3-methylbutanoyl)pyrrolidin-3-yl)(methyl)carbamate (CAS 1354032-73-7)
- 101625-10-9 N-[(phenylmethoxy)carbonyl]-4-bromobutylamine (CAS 101625-10-9)
- Ethyl (3-formyl-4-nitrophenyl) carbonate (CAS 59342-81-3)
- 1,6-Hexamethylenebis(triphenylphosphonium bromide) (CAS 22884-32-8)
- 2-(Ethylamino)oxazole-4-carbonitrile (CAS 2090158-47-5)
- 2-((6-Bromo-2-ethylquinazolin-4-yl)oxy)ethyl acetate (CAS 88642-49-3)
- 2-(4-(N,N-Dipropylsulfamoyl)benzamido)-6-ethyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide (CAS 449767-70-8)
- 3-Methoxy-4-methylpyridazine (CAS 62567-46-8)
- tert-butyl 3-(5-amino-1,3,4-oxadiazol-2-yl)azetidine-1-carboxylate (CAS 1823310-95-7)
- (9-D-Asp) Semaglutide X Sodium salt (CAS CATO-CPTD788617)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com