Chlorphenamine Impurity 20 CAS 4350-41-8
| CAS No. | 4350-41-8 |
| Molecular Formula | C12H10ClN |
| Molecular Weight | 203.67 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Chlorphenamine Impurity 20 (C12H10ClN) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 203.67 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Chlorphenamine Impurity 20 (CAS 4350-41-8) is a certified pharmaceutical impurity reference standard with the molecular formula C12H10ClN and a molecular weight of 203.67 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H10ClN |
| Molecular Weight | 203.67 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorphenamine Standards
- Chlorphenamine Impurity 72 (CAS CATO-C4X-118872)
- Chlorphenamine Impurity 31 (CAS 5005-36-7)
- Chlorphenamine impurity 56 (CAS CATO-C4X-118856)
- Chlorphenamine Impurity 21 (CAS 5005-37-8)
- Chlorphenamine Impurity 25 (CAS 122376-68-5)
- Chlorphenamine impurity 58 (CAS 123517-65-7)
- Chlorphenamine Impurity 60 (CAS 1081516-68-8)
- Chlorphenamine Impurity 30 (CAS CATO-C4X-118830)
Recommended Standards
- Diclofenac Impurity 19 (CAS 1205-40-9)
- 4'-Chloro-Biphenyl-2-yl Amine (CAS 1204-44-0)
- 4-Chloro-N-phenylaniline (CAS 1205-71-6)
- 3-(4-Chloro-1h-pyrazol-1-yl)butanethioamide (CAS 1006320-01-9)
- Semaglutide Impurity 133 (CAS CATO-C4X-2226133)
- Escitalopram EP impurity E D-PTTA (CAS CATO-C4X-110988)
- Sarpogrelate Impurity 8 (CAS CATO-C4X-29138)
- 5-bromo-3-chloro-1H-indazole (CAS 36760-19-7)
- 2-chloro-1-{1H-pyrrolo[2,3-b]pyridin-3-yl}ethan-1-one (CAS 83393-47-9)
- N-(5-bromo-4-(tert-butyl)thiazol-2-yl)-2-chloroacetamide (CAS 887570-77-6)
- 4-((4-(tert-Butyl)phenyl)sulfonamido)benzoic acid (CAS 708996-17-2)
- 2-(3-Fluorophenyl)-2-methylpropanoic acid (CAS 93748-20-0)
- N-Benzyl-3-methoxyaniline (CAS 90811-55-5)
- Tirzepatide Impurity 37 (CAS CATO-C4X-324037)
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