436088-38-9 5-(1-Methyl-cyclopropyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid 5-(1-methylcyclopropyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid CAS 436088-38-9
| CAS No. | 436088-38-9 |
| Molecular Formula | C12H10F3N3O2 |
| Molecular Weight | 285.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
436088-38-9 5-(1-Methyl-cyclopropyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid 5-(1-methylcyclopropyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid (C12H10F3N3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 436088-38-9 5-(1-Methyl-cyclopropyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid 5-(1-methylcyclopropyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 436088-38-9), a certified reference material (molecular formula C12H10F3N3O2, MW 285.22 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 436088-38-9 5-(1-Methyl-cyclopropyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid 5-(1-methylcyclopropyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H10F3N3O2 |
| Molecular Weight | 285.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Methyl Standards
- Methyl 5-cyclopropyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate (CAS 1018142-86-3)
- Methyl 7-cyclopropyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-5-carboxylate (CAS 1795433-31-6)
- Methyl 5-cyclopropyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-7-carboxylate (CAS 1795503-18-2)
- n-Cyclopropyl-4-(3,4-dichlorophenyl)thiazol-2-amine (CAS 1197972-64-7)
- 2-(8-(3-Cyclopropyl-1,2,4-oxadiazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)acetic acid (CAS 1355236-29-1)
- Ethyl 5-cyclopropyl-7-(difluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylate (CAS 832740-92-8)
- N-Cyclopropyl-2-[(6-oxo-1-phenyl-1,6-dihydropyridazin-3-yl)oxy]acetamide (CAS 866131-32-0)
- 5-Cyclopropyl-3-(3,5-dichloro-4-pyridyl)isoxazole-4-methanol (CAS 1020570-04-0)
Recommended Standards
- N-methyl-N-(2-(trifluoromethyl)quinazolin-4-yl)glycine (CAS 927969-23-1)
- 2-Bromo-4,6-di-tert-butylphenol (CAS 20834-61-1)
- n-(4-Amino-3-(trifluoromethyl)phenyl)-5-methylisoxazole-4-carboxamide (CAS 926247-94-1)
- 4-Bromo-2,6-di-tert-butylphenol (CAS 1139-52-2)
- 4-(2,5-dichlorophenoxy)-3-fluoroaniline (CAS 1039869-08-3)
- Osteocalcin (7-19) (human) (CAS 120944-72-1)
- 5-(3,3-Difluoroazetidin-1-yl)-2-nitrobenzaldehyde (CAS 1779120-06-7)
- PHenyl L-Z-Isoleucinamide (CAS 134015-93-3)
- Neostigmine impurity 34 (CAS CATO-C4X-204234)
- (4-(Difluoromethyl)-2-fluoro-5-iodopyridin-3-yl)methanol (CAS 1807134-40-2)
- 2-Ethoxypropyl acetate (CAS 57350-24-0)
- 2-Methoxy-1-(2-(pyrimidin-2-yl)-2,9-diazaspiro[5.5]undecan-9-yl)ethanone (CAS 959524-18-6)
- 8-Hydroxynaphthalene-1-sulfonic acid (CAS 117-22-6)
- α Bag Cell Peptide (1-9) (CAS 87549-52-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com