1-(5-Ethylthiophen-2-yl)-4,4,4-trifluorobutane-1,3-dione CAS 438222-02-7

Purity 97%+In StockPharmaceutical Standards
CAS No.438222-02-7
Molecular FormulaC10H9F3O2S
Molecular Weight250.24 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(5-Ethylthiophen-2-yl)-4,4,4-trifluorobutane-1,3-dione CAS 438222-02-7 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(5-Ethylthiophen-2-yl)-4,4,4-trifluorobutane-1,3-dione.

CATO supplies 1-(5-Ethylthiophen-2-yl)-4,4,4-trifluorobutane-1,3-dione (CAS 438222-02-7), a certified reference material (molecular formula C10H9F3O2S, MW 250.24 g/mol) for analytical method development and quality control.

The molecular framework of 1-(5-Ethylthiophen-2-yl)-4,4,4-trifluorobutane-1,3-dione (C10H9F3O2S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 1-(5-Ethylthiophen-2-yl)-4,4,4-trifluorobutane-1,3-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC10H9F3O2S
Molecular Weight250.24 g/mol
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing
Sulfur Atoms1

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