2-(5-Ethylthiophen-2-yl)-6,8-dimethylquinoline-4-carboxylic acid CAS 438230-08-1
| CAS No. | 438230-08-1 |
| Molecular Formula | C18H17NO2S |
| Molecular Weight | 311.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(5-Ethylthiophen-2-yl)-6,8-dimethylquinoline-4-carboxylic acid (CAS 438230-08-1), molecular formula C18H17NO2S and molecular weight 311.40 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(5-Ethylthiophen-2-yl)-6,8-dimethylquinoline-4-carboxylic acid (C18H17NO2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(5-Ethylthiophen-2-yl)-6,8-dimethylquinoline-4-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H17NO2S |
| Molecular Weight | 311.40 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Ethylthiophen Standards
- 2-(5-Ethylthiophen-2-yl)-7,8-dimethylquinoline-4-carboxylic acid (CAS 895966-56-0)
- 2-(5-Ethylthiophen-2-yl)-6-methylquinoline-4-carboxylic acid (CAS 438216-59-2)
- 4-((5-Ethylthiophen-2-yl)sulfonyl)-2-phenylmorpholine (CAS 946292-18-8)
- 2-(5-Ethylthiophen-2-yl)quinoline-4-carboxylic acid (CAS 351983-35-2)
- 5-(5-Ethylthiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 676624-08-1)
- 3-(1-((5-Ethylthiophen-2-yl)sulfonyl)azetidin-3-yl)thiazolidine-2,4-dione (CAS 1795086-00-8)
- 1-(5-Ethylthiophen-2-yl)-2-(4-nitro-1h-imidazol-1-yl)ethan-1-one (CAS 1197967-97-7)
- 5-(5-Ethylthiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride (CAS 863190-20-9)
Recommended Standards
- 2-((6,7-Dimethyl-2-phenyl-1H-indol-3-yl)thio)acetic acid (CAS 62663-17-6)
- 2-((5,7-Dimethyl-2-phenyl-1H-indol-3-yl)thio)acetic acid (CAS 62663-19-8)
- 2-(Benzo[d]thiazol-2-yl)-N,N-diethylnicotinamide (CAS 873856-45-2)
- 2-((4,7-Dimethyl-2-phenyl-1H-indol-3-yl)thio)acetic acid (CAS 62663-16-5)
- 5-Hydroxy-5-(trifluoromethyl)dihydrofuran-2(3H)-one (CAS 117192-54-8)
- Imazamox (CAS 114311-32-9)
- Tert-butyl 2-cyclopropyl-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxylate (CAS 1395493-08-9)
- N2-[(1R,2S)-2,3-Dihydro-2,6-dimethyl-1H-inden-1-yl]-6-[(1R)-1-fluoroethyl]-1,3,5-triazine-2,4-diamine (CAS 730979-19-8)
- WYE 354-d3 (CAS 1794791-66-4)
- 5-Bromo-3-[2-(pyridin-3-yl)pyrrolidin-1-yl]pyrazin-2-amine (CAS 893612-17-4)
- 4-Amino-2,3-dichlorophenol (CAS 39183-17-0)
- 5-Bromo-2-(isopropylthio)pyrimidine (CAS 433684-22-1)
- 3,4-DIHYDRO-1,5-NAPHTHYRIDIN-2(1H)-ONE (CAS 943537-93-7)
- Semaglutide Main Chain P29 (CAS 1169630-82-3)
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