5-(5-Ethylthiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid CAS 676624-08-1
| CAS No. | 676624-08-1 |
| Molecular Formula | C14H10F3N3O2S |
| Molecular Weight | 341.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 341.31 g/mol gives 5-(5-Ethylthiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-(5-Ethylthiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 676624-08-1), molecular formula C14H10F3N3O2S and molecular weight 341.31 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-(5-Ethylthiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid (C14H10F3N3O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-(5-Ethylthiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H10F3N3O2S |
| Molecular Weight | 341.31 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Ethylthiophen Standards
- 4-((5-Ethylthiophen-2-yl)sulfonyl)-2-phenylmorpholine (CAS 946292-18-8)
- 3-(1-((5-Ethylthiophen-2-yl)sulfonyl)azetidin-3-yl)thiazolidine-2,4-dione (CAS 1795086-00-8)
- 5-(5-Ethylthiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride (CAS 863190-20-9)
- 2-(5-Ethylthiophen-2-yl)-6,8-dimethylquinoline-4-carboxylic acid (CAS 438230-08-1)
- 2-(5-Ethylthiophen-2-yl)-7,8-dimethylquinoline-4-carboxylic acid (CAS 895966-56-0)
- 2-(5-Ethylthiophen-2-yl)-6-methylquinoline-4-carboxylic acid (CAS 438216-59-2)
- 2-(5-Ethylthiophen-2-yl)quinoline-4-carboxylic acid (CAS 351983-35-2)
- 1-(5-Ethylthiophen-2-yl)-2-(4-nitro-1h-imidazol-1-yl)ethan-1-one (CAS 1197967-97-7)
Recommended Standards
- 4-Acetamidophenyl -β-D-Glucuronic Acid Methyl Ester (CAS 570394-17-1)
- 5-Methyl-3-(phenylsulfonyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine (CAS 685107-44-2)
- 4-(2-(3-Nitrophenoxy)ethoxy)benzene-1-sulfonyl fluoride (CAS 31185-40-7)
- Ethyl 5-(thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate (CAS 333762-01-9)
- 3-((4-Fluorophenyl)thio)-1-(thiophen-2-yl)propan-1-one (CAS 477334-42-2)
- N-(1-(pyridin-4-yl)ethyl)cyclohexanamine (CAS 1019594-24-1)
- 2-Chloro-5,8-difluoroquinoline (CAS 773148-82-6)
- 3-(Decyloxy)tetrahydrothiophene 1,1-dioxide (CAS 18760-44-6)
- cis-2-methyloxetan-3-ol (CAS 126822-52-4)
- 7-Bromo-6-chloro-1H-imidazo[4,5-c]pyridine (CAS 1446449-86-0)
- N-Butyl-N-(4-methyloxazol-2-yl)-4-nitrobenzamide (CAS 57067-90-0)
- (2S,6S)-1,2,6-trimethylpiperazine;dihydrochloride (CAS 2126143-60-8)
- 6,11-dibromo-1,4-diazatriphenylene (CAS 1012836-59-7)
- Semaglutide impurity 40 (CAS CATO-C4X-222640)
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