2-Amino-N-(4-chlorophenyl)-4-ethyl-5-methylthiophene-3-carboxamide CAS 438231-19-7
| CAS No. | 438231-19-7 |
| Molecular Formula | C14H15ClN2OS |
| Molecular Weight | 294.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Amino-N-(4-chlorophenyl)-4-ethyl-5-methylthiophene-3-carboxamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-Amino-N-(4-chlorophenyl)-4-ethyl-5-methylthiophene-3-carboxamide (CAS 438231-19-7), a certified reference material (molecular formula C14H15ClN2OS, MW 294.80 g/mol) for analytical method development and quality control.
The molecular framework of 2-Amino-N-(4-chlorophenyl)-4-ethyl-5-methylthiophene-3-carboxamide (C14H15ClN2OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H15ClN2OS |
| Molecular Weight | 294.80 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 2-Amino-N-(3-chlorophenyl)-4-ethyl-5-methylthiophene-3-carboxamide (CAS 588714-51-6)
- [1-(2-Amino-ethyl)-piperidin-3-ylmethyl]-benzyl-cyclopropyl-amine (CAS 1353987-91-3)
- (S)-2-Amino-N-[1-(3-chloro-phenyl)-ethyl]-N-isopropyl-3-methyl-butyramide (CAS 1354028-83-3)
- 2-Amino-N-((S)-1-(3-chlorophenyl)ethyl)-N-cyclopropyl-3-methylbutanamide (CAS 1354032-95-3)
- 4-(5-Amino-1,3,4-thiadiazol-2-yl)-1-(4-chlorophenyl)pyrrolidin-2-one (CAS 1142202-39-8)
- Methyl 3-amino-4-[(5-chloropyridin-2-yl)sulfanyl]benzoate (CAS 1379272-52-2)
- 2-Amino-N-(3-(2-chlorobenzoyl)thiophen-2-yl)acetamide (CAS 36811-56-0)
- (3-Amino-2,6-dibromophenyl)boronic acid (CAS 1227633-22-8)
Recommended Standards
- 2-Chloro-5-((4-(pyridin-2-yl)piperazin-1-yl)methyl)thiazole (CAS 865660-09-9)
- 2-(4-Chlorophenyl)-3-methyl-N-(thiazol-2-yl)butanamide (CAS 300851-67-6)
- 2-Chloro-n-[4-(2,4,5-trimethylphenyl)-1,3-thiazol-2-yl]acetamide (CAS 733796-12-8)
- 2-(4-Chloro-3-methylphenyl)-3-thioxohexahydroimidazo[1,5-a]pyridin-1(5H)-one (CAS 60726-03-6)
- 3-Tert-butyl-1-methyl-1h-pyrazolo[3,4-b]pyridine-5-carboxylic acid (CAS 926257-81-0)
- (5-((4-Bromophenyl)thio)-1-methyl-3-phenyl-1H-pyrazol-4-yl)methanol (CAS 318247-56-2)
- (Chloromethyl)cycloheptane (CAS 99969-52-5)
- 2-(3,5-Dichlorobenzoyl)benzoic acid (CAS 33184-61-1)
- Methyl 3-acetamido-4,5-dichlorothiophene-2-carboxylate (CAS 632356-39-9)
- 6-Bromo-3-chloro-2-fluorophenylboronic acid pinacol ester (CAS 1451391-14-2)
- 1H-pyrazolo[4,3-d]pyrimidine-5-carboxylic acid (CAS 2125678-94-4)
- Ethyl 5H-Pyrrolo[3,4-b]pyridine-6(7H)-carboxylate (CAS 147740-01-0)
- Sertraline Acetamide (CAS 1097616-52-8)
- TRAF6 Control Peptide trifluoroacetate salt (CAS 852690-80-3)
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