6-Bromo-2-(4-chlorophenyl)-3-methylquinoline-4-carboxylic acid CAS 438531-53-4
| CAS No. | 438531-53-4 |
| Molecular Formula | C17H11BrClNO2 |
| Molecular Weight | 376.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
6-Bromo-2-(4-chlorophenyl)-3-methylquinoline-4-carboxylic acid (CAS 438531-53-4) is a high-purity analytical reference standard with the molecular formula C17H11BrClNO2 and a molecular weight of 376.63 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, 6-Bromo-2-(4-chlorophenyl)-3-methylquinoline-4-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 376.63 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C17H11BrClNO2 |
| Molecular Weight | 376.63 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 6-Bromo-2-(3-methoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160265-00-8)
- 6-Bromo-2-(4-methoxyphenyl)quinoline-4-carbonyl chloride (CAS 148122-02-5)
- 6-Bromo-7-chloro-8-methyl-2-phenylquinoline-4-carboxylic acid (CAS 894552-27-3)
- N-(4-Bromo-2-fluorophenyl)-5-chloro-2-(methylthio)pyrimidine-4-carboxamide (CAS 898648-45-8)
- 6-Bromo-4-((3-chloro-4-fluorophenyl)amino)quinoline-3-carbonitrile (CAS 915369-04-9)
- 8-(2-(4-Bromo-2-chlorophenoxy)ethyl)-1,4-dioxa-8-azaspiro[4.5]Decane (CAS 1704080-53-4)
- Methyl 4-bromo-2,3-difluoro-5-iodobenzoate (CAS 1878217-46-9)
- 3-Bromo-2-thiomorpholinomethyl benzophenone (CAS 898781-70-9)
Recommended Standards
- 2-(4-Bromophenyl)-7-chloro-8-methylquinoline-4-carboxylic acid (CAS 588696-21-3)
- 2-(3-Bromophenyl)-7-chloro-8-methylquinoline-4-carboxylic acid (CAS 777876-90-1)
- N-(2-Bromophenyl)-5-(2-chlorophenyl)furan-2-carboxamide (CAS 618400-86-5)
- N-(2-Bromophenyl)-5-(4-chlorophenyl)furan-2-carboxamide (CAS 461398-39-0)
- Ponesimod (CAS 854107-55-4)
- 5-(Chloromethyl)benzo[d]oxazole (CAS 1201648-09-0)
- (E)-5-Fluorothiophene-2-carbaldehyde oxime (CAS 34746-11-7)
- Methyl 2-((dimethylamino)methyl)oxazole-4-carboxylate (CAS 1026278-25-0)
- 1-(o-Tolyl)-1H-1,2,3-triazole-5-carboxylic acid (CAS 1153905-10-2)
- Non-3-yne (CAS 20184-89-8)
- 1-(3-(Aminomethyl)phenyl)ethanone (CAS 748104-67-8)
- 1-(4-Bromo-2-fluorophenyl)-3-(cyclopropylmethyl)urea (CAS 1211296-24-0)
- Lenvatinib Impurity 54 (CAS 2143930-77-0)
- Semaglutide impurity 198 (CAS CATO-C4X-2226198)
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