2-Amino-5-(3,5-difluorophenyl)pyridine CAS 438585-72-9

Purity 97%+In StockPharmaceutical Standards
CAS No.438585-72-9
Molecular FormulaC11H8F2N2
Molecular Weight206.19 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Amino-5-(3,5-difluorophenyl)pyridine CAS 438585-72-9 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 206.19 g/mol gives 2-Amino-5-(3,5-difluorophenyl)pyridine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 2-Amino-5-(3,5-difluorophenyl)pyridine (CAS 438585-72-9), a certified reference material (molecular formula C11H8F2N2, MW 206.19 g/mol) for analytical method development and quality control.

The molecular framework of 2-Amino-5-(3,5-difluorophenyl)pyridine (C11H8F2N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC11H8F2N2
Molecular Weight206.19 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing
Nitrogen Atoms2

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