N-[(4-Chlorophenyl)methyl]-1-cyclohexyl-6-oxo-2-phenylpiperidine-3-carboxamide CAS 439111-06-5
| CAS No. | 439111-06-5 |
| Molecular Formula | C25H29ClN2O2 |
| Molecular Weight | 424.96 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-[(4-Chlorophenyl)methyl]-1-cyclohexyl-6-oxo-2-phenylpiperidine-3-carboxamide.
N-[(4-Chlorophenyl)methyl]-1-cyclohexyl-6-oxo-2-phenylpiperidine-3-carboxamide (CAS 439111-06-5) is a high-purity analytical reference standard with the molecular formula C25H29ClN2O2 and a molecular weight of 424.96 g/mol.
Structurally, N-[(4-Chlorophenyl)methyl]-1-cyclohexyl-6-oxo-2-phenylpiperidine-3-carboxamide (C25H29ClN2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 424.96 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-[(4-Chlorophenyl)methyl]-1-cyclohexyl-6-oxo-2-phenylpiperidine-3-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H29ClN2O2 |
| Molecular Weight | 424.96 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related N Standards
- 1-{[({2-[(4-chlorophenyl)sulfanyl]phenyl}methyl)sulfanyl]methyl}-3-(trifluoromethyl)benzene (CAS 337923-77-0)
- 1-((4-Chlorophenyl)sulfonyl)-3,5-dimethyl-4-((phenylsulfonyl)methyl)-1H-pyrazole (CAS 321574-42-9)
- 2-(4-Chlorophenyl)-5-{2-[(4-methylphenyl)methanesulfonyl]phenyl}-1,3,4-oxadiazole (CAS 339104-33-5)
- 1-(4-{4-[5-(4-chlorophenyl)-1H-pyrazol-3-yl]piperidin-1-yl}-3-nitrophenyl)ethan-1-one (CAS 1030856-24-6)
- 2-{[(4-chlorophenyl)carbamoyl]amino}-2-phenylethyl 4-methoxybenzoate (CAS 343373-26-2)
- 4-((4-Chlorophenyl)sulfonyl)-2-(2-fluorophenyl)-N-(3-methoxypropyl)oxazol-5-amine (CAS 823829-89-6)
- 2-((2-(4-Chlorophenyl)-2-oxoethyl)thio)-3-phenyl-6-(trifluoromethyl)pyrimidin-4(3H)-one (CAS 692287-35-7)
- 6-(2-Chlorophenyl)-2-(naphthalen-2-yloxy)-4-(trifluoromethyl)pyridine-3-carbonitrile (CAS 478049-44-4)
Recommended Standards
- Sotagliflozin (CAS 1018899-04-1)
- Epinastine Impurity 47 (CAS CATO-C4X-184047)
- Osimertinib Impurity 3 (AZD9291 Impurity 3) (CAS CATO-C4X-20453)
- 1-(((4-(5-Chloro-2-methylphenyl)piperazin-1-yl)sulfonyl)methyl)-7,7-dimethylbicyclo[2.2.1]Heptan-2-one (CAS 1022130-08-0)
- Methyl 1-(2,2-difluoroethyl)-1H-pyrazole-5-carboxylate (CAS 1172234-95-5)
- Methyl 1-Methylimidazole-4-carboxylate (CAS 17289-19-9)
- 3-Bromo-6-methoxy-8-nitroquinoline (CAS 95836-48-9)
- 6-Chloro-N-phenyl-2,3,4,9-tetrahydro-1H-carbazol-1-amine (CAS 812649-15-3)
- (S)-2-Amino-N-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methyl)-N-isopropyl-3-methylbutanamide (CAS 1354017-27-8)
- 3-Azabicyclo[3.1.0]Hexane-6-carboxylic acid (CAS 1018721-85-1)
- (1r,4r)-4-[(3-chloropyridin-2-yl)oxy]cyclohexan-1-amine dihydrochloride (CAS 2059909-60-1)
- Linezolid Impurity 69 (CAS 10389-51-2)
- 5-Iodo-7-methylbenzofuran (CAS 799766-26-0)
- Tirzepatide Impurity 47 (CAS CATO-C4X-324047)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com