N-[3-Fluoro-4-(4-phenylpiperazin-1-yl)phenyl]-2-(piperidin-1-yl)acetamide CAS 439120-46-4
| CAS No. | 439120-46-4 |
| Molecular Formula | C23H29FN4O |
| Molecular Weight | 396.50 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of N-[3-Fluoro-4-(4-phenylpiperazin-1-yl)phenyl]-2-(piperidin-1-yl)acetamide is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
N-[3-Fluoro-4-(4-phenylpiperazin-1-yl)phenyl]-2-(piperidin-1-yl)acetamide (CAS 439120-46-4) is a high-purity analytical reference standard with the molecular formula C23H29FN4O and a molecular weight of 396.50 g/mol.
The molecular framework of N-[3-Fluoro-4-(4-phenylpiperazin-1-yl)phenyl]-2-(piperidin-1-yl)acetamide (C23H29FN4O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-[3-Fluoro-4-(4-phenylpiperazin-1-yl)phenyl]-2-(piperidin-1-yl)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H29FN4O |
| Molecular Weight | 396.50 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related N Standards
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- 2-(4-{3-fluoro-4'-[(1-hydroxypropan-2-yl)oxy]-[1,1'-biphenyl]-4-yl}phenoxy)propan-1-ol (CAS 477860-07-4)
- 2-Fluoro-4-[2-(4-propylcyclohexyl)ethyl]phenyl trifluoromethanesulfonate (CAS 477860-09-6)
- 3-Fluoro-4-methoxy-N-(1-(3-(pyridin-3-yl)-1,2,4-oxadiazol-5-yl)cyclohexyl)benzamide (CAS 1340842-38-7)
- Methyl 7-(5-fluoro-2-methoxyphenyl)-2-(methylsulfonyl)thieno[3,2-d]pyrimidine-6-carboxylate (CAS 1462950-10-2)
- 3-[1-(3-Fluoro-4-methoxybenzoyl)piperidin-4-yl]-4-phenyl-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775412-11-7)
- 4-((4-Fluoro-2-methyl-1H-indol-5-yl)oxy)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl pivalate (CAS 952490-01-6)
- (2-Ethyl-5-fluoro-4-((2-(trimethylsilyl)ethoxy)methoxy)benzene)boronic acid pinacol ester, 97% (CAS 1421503-40-3)
Recommended Standards
- N-(4-butylphenyl)-2-((4-(2,5-dioxopyrrolidin-1-yl)phenyl)thio)acetamide (CAS 763108-58-3)
- Z-ILE-MET-OH (CAS 84030-22-8)
- N-(2-aminoethyl)-N-(4-(benzyloxy)-3-methoxybenzyl)thiophene-2-carboxamide (CAS 884049-35-8)
- 71116-82-0 98E50HHH7M Tiaprost [INN:BAN] 5-Heptenoic acid, 7-(3,5-dihydroxy-2-(3-hydroxy-4-(3-thienyloxy)-1-butenyl)cyclopentyl)- Iliren Tiaprost Tiaprostum [INN-Latin] (+-)-(Z)-7-((1R*,2R*,3R*,5S)-3,5-Dihydroxy-2-((E)-(3R*,S*)-3-hydroxy-4-(3-thienyloxy)-1-butenyl)cyclopentyl)-5-heptenoic acid (+-)-(Z)-7-((1R*,2R*,3R*,5S*)-3,5-Dihydroxy-2-((E)-(3R*S*)-3-hydroxy-4-(3-thienyloxy)-1-butenyl)cyclopentyl)-5-heptenoic acid Tiaprostum UNII-98E50HHH7M (CAS 71116-82-0)
- N-(4-aminophenyl)-1-ethyl-1H-pyrazole-3-carboxamide (CAS 1004194-64-2)
- 1-Acetyl-5-aminoindolin-2-one (CAS 422518-10-3)
- 2,5-Bis(trifluoromethyl)benzyl chloride (CAS 911060-71-4)
- Samarium(III) Carbonate Hydrate (CAS 38245-37-3)
- 3-(4-Methoxyphenyl)-N-(4-methylphenyl)-2-(2H-1,2,3,4-tetrazol-5-yl)propanamide (CAS 483993-01-7)
- 1-(4-Chlorophenyl)-3-Fluoropropan-2-Amine (CAS 76605-09-9)
- (S)-2-Amino-N-(2,5-dichlorobenzyl)propanamide (CAS 1354001-13-0)
- Glycerol Impurity 32 (CAS CATO-C4X-217132)
- 2-Chloro-1-(5-chloro-2-hydroxyphenyl)ethanone (CAS 24483-75-8)
- Semaglutide impurity 55 (CAS CATO-C4X-222655)
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