2-((2-Chlorobenzyl)thio)benzoic acid CAS 440347-30-8
| CAS No. | 440347-30-8 |
| Molecular Formula | C14H11ClO2S |
| Molecular Weight | 278.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-((2-Chlorobenzyl)thio)benzoic acid (CAS 440347-30-8), molecular formula C14H11ClO2S and molecular weight 278.75 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-((2-Chlorobenzyl)thio)benzoic acid (C14H11ClO2S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 2-((2-Chlorobenzyl)thio)benzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H11ClO2S |
| Molecular Weight | 278.75 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related Chlorobenzyl Standards
- 2-((4-Chlorobenzyl)thio)benzoic acid (CAS 15887-84-0)
- 2-(4-Chlorobenzyl)-2,8-diazaspiro[4.5]decan-3-one (CAS 1258000-09-7)
- 5-((4-Chlorobenzyl)oxy)-2-hydroxybenzoic acid (CAS 1215858-20-0)
- 5-[(2-chlorobenzyl)oxy]-2-hydroxybenzoic acid (CAS 16094-45-4)
- 5-((3-Chlorobenzyl)oxy)-2-hydroxybenzoic acid (CAS 16094-46-5)
- 1-(3-Chlorobenzyl)piperidin-3-amine hydrochloride (CAS 1261231-91-7)
- 5-((4-Chlorobenzyl)oxy)-4-oxo-1,4-dihydropyridine-2-carboxylic acid (CAS 1269528-47-3)
- 5-((3-Chlorobenzyl)oxy)-4-oxo-1,4-dihydropyridine-2-carboxylic acid (CAS 1269534-73-7)
Recommended Standards
- 2-(Benzylthio)-4-chlorobenzoic Acid (CAS 40183-35-5)
- 2-(2-((4-Chlorophenyl)thio)phenyl)acetic acid (CAS 13459-62-6)
- 2-[(2-chlorophenyl)sulfanyl]-2-phenylacetic acid (CAS 938267-73-3)
- 4-(3-Methoxyphenoxy)butane-1-sulfonyl chloride (CAS 1343441-15-5)
- (S)-2-Amino-5-phenylpent-4-enoic acid (CAS 267650-37-3)
- 1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-5-methylpiperidine-3-carboxylic acid (CAS 1936540-49-6)
- 2-Amino-6-chloro-N-(2-methoxyethyl)-4-oxo-4H-chromene-3-carboxamide (CAS 883279-34-3)
- Diltiazem - Impurity C (Freebase) (CAS 84903-78-6)
- Cariprazine Impurity 39 (CAS CATO-C4X-240839)
- 4,4-difluoro-2-methylbutan-1-amine hydrochloride (CAS 1909314-14-2)
- 4,4'-((5-Fluorobenzo[c][1,2,5]thiadiazole-4,7-diyl)bis(ethyne-2,1-diyl))dibenzaldehyde (CAS 2460375-94-2)
- 3-Hydroxypyrrolidine-1-carboximidamide sulfate (CAS 1056471-60-3)
- Pyrrolidine-2,5-dicarboxylic acid (CAS 72000-65-8)
- Semaglutide impurity 233 (CAS CATO-C4X-2226233)
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