Levocetirizine Impurity 44 CAS 442863-80-1
| CAS No. | 442863-80-1 |
| Molecular Formula | C21H25ClN2O4 |
| Molecular Weight | 404.89 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 404.89 g/mol gives Levocetirizine Impurity 44 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Levocetirizine Impurity 44 (CAS 442863-80-1), a pharmacopoeial impurity reference standard (molecular formula C21H25ClN2O4, MW 404.89 g/mol) used for the identification and quantification of trace impurities in APIs.
Levocetirizine Impurity 44 (C21H25ClN2O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Levocetirizine Impurity 44 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H25ClN2O4 |
| Molecular Weight | 404.89 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Levocetirizine Standards
- Levocetirizine Impurity 70 (CAS CATO-C4X-108370)
- Levocetirizine Impurity 42 (CAS CATO-C4X-108342)
- Levocetirizine Impurity 8 (CAS 83881-46-3)
- Levocetirizine Impurity 53 (CAS CATO-C4X-108353)
- Levocetirizine Impurity 11 (CAS 246870-46-2)
- Levocetirizine Impurity 43 (CAS 1116338-10-3)
- Levocetirizine Impurity 35 (CAS 130018-76-7)
- Levocetirizine Impurity 69 (CAS CATO-C4X-108369)
Recommended Standards
- rac Cetirizine N-Oxide (Mixture of Diastereomers) (CAS 1076199-80-8)
- N-(3-Chloro-4-fluorophenyl)-4-hydroxy-1-methyl-1H-thieno[3,2-c][1,2]thiazine-3-carbothioamide 2,2-dioxide (CAS 320423-78-7)
- Bepotastine N-Oxide Impurity (CAS CATO-C4X-18391)
- 4-[(2E)-3-(Thiophen-2-yl)prop-2-enoyl]phenyl 4-chlorobenzene-1-sulfonate (CAS 331460-91-4)
- Crisaborole lmpurity 76 (CAS 2227126-09-0)
- Trazodone Impurity 69 (CAS CATO-C4X-177269)
- Tolbutamide EP Impurity B (CAS 1694-06-0)
- 6-fluoro-2,3-dihydroxybenzoic acid (CAS 492444-05-0)
- 1-Methoxy-3-phenylcyclohepta[c]phosphole (CAS 87509-02-2)
- 5-Formyl-2-(piperidin-1-yl)benzonitrile (CAS 1272756-59-8)
- 2-(Methylsulfonyl)-1-(4-nitrophenyl)ethan-1-one (CAS 136819-50-6)
- (2R,3S,5R)-5-(2-Amino-4-chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol (CAS 104291-17-0)
- Pyronaridine Impurity 20 (CAS CATO-C4X-297820)
- (β-Asp5)-Delta-Sleep Inducing Peptide (CAS 82602-88-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com