Valsartan Impurity 42 CAS 443093-86-5
| CAS No. | 443093-86-5 |
| Molecular Formula | C24H28N2O3 |
| Molecular Weight | 392.49 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Valsartan Impurity 42 (CAS 443093-86-5), a pharmacopoeial impurity reference standard (molecular formula C24H28N2O3, MW 392.49 g/mol) used for the identification and quantification of trace impurities in APIs.
Valsartan Impurity 42 (C24H28N2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H28N2O3 |
| Molecular Weight | 392.49 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >80% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
Related Valsartan Standards
- Valsartan Impurity 126 (CAS CATO-C4X-1057126)
- Valsartan Impurity 111 (CAS CATO-C4X-1057111)
- Valsartan Impurity 48 (CAS 1314799-74-0)
- Valsartan Impurity 137 (CAS CATO-C4X-1057137)
- Valsartan Impurity 138 (CAS CATO-C4X-1057138)
- Valsartan Impurity 135 (CAS CATO-C4X-1057135)
- Valsartan Impurity 67 (CAS 2254485-68-0)
- Valsartan impurity 19 (CAS CATO-C4X-105719)
Recommended Standards
- Carfilzomib Impurity 82 (CAS CATO-C4X-102282)
- Risperidone EP Impurity K (CAS 106266-09-5)
- Xanthoangelol (CAS 62949-76-2)
- S-Indacaterol (CAS 1235445-80-3)
- (RR+SS)-Formoterol Impurity 79 Hemifumarate (CAS 143687-24-5)
- Finerenone Impurity 154 (CAS CATO-C4X-2880154)
- Dorzolamide Impurity 11 (and enantiomer) (CAS CATO-C4X-122811)
- Disodium 3-Hydroxy-2,7-naphthalenedisulfonate (CAS 135-51-3)
- Dimethyl 2-diazomalonate (CAS 6773-29-1)
- 1-Hexadecene (CAS 629-73-2)
- 3-Methyl-N-(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)butanamide (CAS 2246681-91-2)
- Methyl 5-iodobenzo[b]thiophene-2-carboxylate (CAS 146137-90-8)
- N-[(1-Butyl-1,2,3,4-tetrahydroquinolin-6-yl)-methyl]-N-(2-furylmethyl)amine (CAS 1119453-02-9)
- Semaglutide impurity 210 (CAS CATO-C4X-2226210)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com