3-((5-(5-Bromo-2-hydroxybenzylidene)-3-methyl-4-oxothiazolidin-2-ylidene)amino)benzoic acid CAS 443877-67-6
| CAS No. | 443877-67-6 |
| Molecular Formula | C18H13BrN2O4S |
| Molecular Weight | 433.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 433.28 g/mol gives 3-((5-(5-Bromo-2-hydroxybenzylidene)-3-methyl-4-oxothiazolidin-2-ylidene)amino)benzoic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 3-((5-(5-Bromo-2-hydroxybenzylidene)-3-methyl-4-oxothiazolidin-2-ylidene)amino)benzoic acid (CAS 443877-67-6), a certified reference material (molecular formula C18H13BrN2O4S, MW 433.28 g/mol) for analytical method development and quality control.
The molecular framework of 3-((5-(5-Bromo-2-hydroxybenzylidene)-3-methyl-4-oxothiazolidin-2-ylidene)amino)benzoic acid (C18H13BrN2O4S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-((5-(5-Bromo-2-hydroxybenzylidene)-3-methyl-4-oxothiazolidin-2-ylidene)amino)benzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H13BrN2O4S |
| Molecular Weight | 433.28 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Bromo Standards
- (2E)-3-(6-Bromo-2H-1,3-benzodioxol-5-yl)-1-[4-(2-fluorophenyl)piperazin-1-yl]prop-2-en-1-one (CAS 478078-33-0)
- 2-(4-(3-Acetyl-8-bromo-3H-pyrazolo[3,4-c]quinolin-1-yl)phenyl)-2-methylpropanenitrile (CAS 1201643-72-2)
- N-(4-bromo-3-methylphenyl)-2-(4-(4-nitrophenyl)piperazin-1-yl)acetamide (CAS 882080-37-7)
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- 4-((3-Bromo-4-methoxybenzylidene)amino)-3-(3-ethoxyphenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 613249-85-7)
- 4-((5-Bromo-2-methoxybenzylidene)amino)-3-(3-ethoxyphenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 497921-65-0)
- 23-Bromo-3,6,9,12,15,18,21-heptaoxatricosan-1-ol (CAS 1527515-88-3)
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Recommended Standards
- 1-(2,4-Dichlorobenzyl)-N-(3,5-dimethoxyphenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (CAS 320419-83-8)
- 5-((6-(4-Bromophenyl)imidazo[2,1-b]thiazol-5-yl)methylene)-2,2-dimethyl-1,3-dioxane-4,6-dione (CAS 439107-47-8)
- 1-(2,4-Dichlorobenzyl)-N-(3,4-dimethoxyphenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (CAS 320419-63-4)
- Benzyl N-Boc-3-amino-5-iodopentanoate (CAS 643044-91-1)
- 2-(2-Furyl)-1,3-oxazole-4-carboxylic acid (CAS 927800-86-0)
- N-(p-Tolyl)morpholine-3-carboxamide (CAS 1479757-96-4)
- 2-(1H-imidazol-2-yl)propan-2-amine dihydrochloride (CAS 1909317-10-7)
- Methylmalonic acid (dipotassium) (CAS 77939-79-8)
- 1-(2-Ethylbenzofuran-3-yl)-N-methylmethanamine (CAS 91639-76-8)
- 3-(2,2,2-Trifluoroethyl)-2,5-dihydro-1H-pyrrole hydrochloride (CAS 2493236-44-3)
- Sarpogrelate hydrochloride (CAS 135159-51-2)
- (r)-3-Formamido-3-(furan-2-yl)propanoic acid (CAS 1344943-58-3)
- 3-methyloxolan-3-amine hydrochloride (CAS 1423034-45-0)
- Insulin Degludec Impurity 14 (CAS CATO-C4X-215714)
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