2-(4-(3-Acetyl-8-bromo-3H-pyrazolo[3,4-c]quinolin-1-yl)phenyl)-2-methylpropanenitrile CAS 1201643-72-2
| CAS No. | 1201643-72-2 |
| Molecular Formula | C22H17BrN4O |
| Molecular Weight | 433.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(4-(3-Acetyl-8-bromo-3H-pyrazolo[3,4-c]quinolin-1-yl)phenyl)-2-methylpropanenitrile (CAS 1201643-72-2), molecular formula C22H17BrN4O and molecular weight 433.30 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(4-(3-Acetyl-8-bromo-3H-pyrazolo[3,4-c]quinolin-1-yl)phenyl)-2-methylpropanenitrile (C22H17BrN4O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(4-(3-Acetyl-8-bromo-3H-pyrazolo[3,4-c]quinolin-1-yl)phenyl)-2-methylpropanenitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H17BrN4O |
| Molecular Weight | 433.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 4 |
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Recommended Standards
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- 1,4-Dihydro-5-[5-bromoacetyl)-2-ethoxyphenyl]-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one (CAS 147676-94-6)
- Empagliflozin Impurity 171 (CAS CATO-C4X-1065171)
- (2E)-4,4,4-Trifluoro-N-(4-methoxyphenyl)-3-oxo-2-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}butanamide (CAS 866130-99-6)
- thenyldiaminehydrochloride (CAS 958-93-0)
- 3-(Benzyloxy)picolinaldehyde (CAS 94454-57-6)
- 6,7-Dimethoxy-3,4-dihydroisoquinoline-1(2H)-thione (CAS 24456-59-5)
- (S)-Bn-iQuinox (CAS 2058236-52-3)
- 2-Iodo-5-phenylthiophene (CAS 13781-37-8)
- S-p-Tolyl 4-(benzo[d]oxazol-2-yl)benzothioate (CAS 62572-76-3)
- 1-(2,4-Dichlorobenzyl)-1h-indole-3-carbaldehyde (CAS 90815-03-5)
- Tert-butyl (1-(3-methyl-1,2,4-oxadiazol-5-yl)cyclopropyl)carbamate (CAS 1159736-56-7)
- 5-Methyl-2-(2,2,2-trifluoroacetamido)thiophene-3-carboxylic acid (CAS 1082186-04-6)
- Ganirelix 1-4 peptide (CAS 208599-57-9)
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