1-(7-Amino-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)butan-1-one CAS 444111-26-6

Purity 97%+In StockPharmaceutical Standards
CAS No.444111-26-6
Molecular FormulaC12H15NO3
Molecular Weight221.25 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(7-Amino-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)butan-1-one CAS 444111-26-6 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 221.25 g/mol gives 1-(7-Amino-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)butan-1-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

1-(7-Amino-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)butan-1-one (CAS 444111-26-6), molecular formula C12H15NO3 and molecular weight 221.25 g/mol, is a CATO reference standard with documented purity and traceability.

1-(7-Amino-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)butan-1-one (C12H15NO3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1-(7-Amino-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)butan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H15NO3
Molecular Weight221.25 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Nitrogen Atoms1

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