3-Acetyl-6-bromoquinoline-4-carboxylic acid CAS 444112-84-9
| CAS No. | 444112-84-9 |
| Molecular Formula | C12H8BrNO3 |
| Molecular Weight | 294.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 3-Acetyl-6-bromoquinoline-4-carboxylic acid (CAS 444112-84-9), a certified reference material (molecular formula C12H8BrNO3, MW 294.10 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution, 3-Acetyl-6-bromoquinoline-4-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 294.10 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H8BrNO3 |
| Molecular Weight | 294.10 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Acetyl Standards
- 4-Bromoquinoline-3,8-dicarboxylic acid (CAS 1378259-53-0)
- 4-Bromoquinoline-3,7-dicarboxylic acid (CAS 1378259-65-4)
- 6-Bromoquinoline-2,3-dicarboxylic acid (CAS 92513-49-0)
- 6-Bromoquinoline-2,4-dicarboxylic acid (CAS 250641-14-6)
- 7-Bromoquinoline-2,3-dicarboxylic acid (CAS 892874-38-3)
- 8-Bromoquinoline-2,4-dicarboxylic acid (CAS 216060-06-9)
- ethyl 4-bromoquinoline-6-carboxylate (CAS 958332-97-3)
- 5-Bromoquinoline-8-sulfonic acid (CAS 804430-48-6)
Recommended Standards
- 2-Bromo-6-nitro-4-(pyridin-3-yl)aniline (CAS 797047-13-3)
- 4-(3-Bromobenzoyl)-1H-pyrrole-2-carboxylic acid (CAS 924868-86-0)
- 2-(4-Bromophenyl)-5-(2-nitrovinyl)furan (CAS 56297-20-2)
- 4-[(5-bromopyridin-2-yl)oxy]benzoic acid (CAS 58835-85-1)
- 2,4,6-Trichloro-5-iodopyrimidine (CAS 1137576-61-4)
- (E)-1-(3,5-Difluoropyridin-2-yl)-2-methoxyethanone oxime (CAS 1075757-31-1)
- [1,1'-Biphenyl]-4-ylchlorodimethylsilane (CAS 41081-31-6)
- 4-(Chloromethyl)-2-(2-thienyl)thiazole (CAS 54679-16-2)
- (5-Bromo-2-(methylthio)pyrimidin-4-yl)methyl methanesulfonate (CAS 1481616-19-6)
- 2-((2,6-Dichlorobenzyl)oxy)benzaldehyde (CAS 175203-16-4)
- Potassium 2,2'-oxybis(1,1,2,2-tetrafluoroethanesulfonate) (CAS 104820-46-4)
- 1,1-Diphenyl-1-pentanol (CAS 5384-63-4)
- 4-Methoxypyridin-2(1H)-one (CAS 52545-13-8)
- Semaglutide Impurity 144 (CAS 394210-59-4)
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