2,5-Dimethyl-1-{2-[7-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-2-yl]thiophen-3-yl}-1H-pyrrole CAS 444151-85-3
| CAS No. | 444151-85-3 |
| Molecular Formula | C23H20N4S |
| Molecular Weight | 384.50 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,5-Dimethyl-1-{2-[7-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-2-yl]thiophen-3-yl}-1H-pyrrole (CAS 444151-85-3), molecular formula C23H20N4S and molecular weight 384.50 g/mol, is a CATO reference standard with documented purity and traceability.
2,5-Dimethyl-1-{2-[7-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-2-yl]thiophen-3-yl}-1H-pyrrole (C23H20N4S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H20N4S |
| Molecular Weight | 384.50 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Dimethyl Standards
- 2,5-Dimethyl-1-(2-{5-methyl-7-phenylpyrazolo[1,5-a]pyrimidin-2-yl}thiophen-3-yl)-1H-pyrrole (CAS 866049-48-1)
- 2,5-Dimethyl-1-{2-[6-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-2-yl]thiophen-3-yl}-1H-pyrrole (CAS 691884-05-6)
- 4,6-Dimethyl-2-{4-[(4-methylphenyl)sulfonyl]-1,4-diazepan-1-yl}nicotinonitrile (CAS 478256-89-2)
- 2-[2,6-Dimethyl-4-[3-[4-(methylthio)phenyl]-3-oxo-1-propen-1-yl]phenoxy]-2-methylpropionic Acid (CAS 824932-88-9)
- Methyl 2-{[4-(2,5-dimethyl-1H-pyrrol-1-yl)phenyl]sulfamoyl}benzoate (CAS 866156-46-9)
- 2,5-Dimethyl-N1,N4-diphenylpiperazine-1,4-bis(carbothioamide) (CAS 74010-61-0)
- 3',3'-Dimethyl-6-nitro-1'-phenylspiro[chromene-2,2'-indoline] (CAS 14538-13-7)
- Dimethyl 2-(5-(4-(tert-butyl)benzamido)pyridin-2-yl)malonate (CAS 861209-83-8)
Recommended Standards
- 4-(3-(3-(Triethoxysilyl)propyl)ureido)benzoic acid (CAS 496853-15-7)
- 2-(4-(Benzylsulfonyl)-1,4-diazepan-1-yl)-4,6-dimethylnicotinonitrile (CAS 866136-69-8)
- 4-O-tert-Butyldimethylsilyl Genistein (CAS 470666-97-8)
- 2-(2-{4-[2-(methylsulfanyl)phenyl]piperazin-1-yl}ethyl)-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-3-one (CAS 860651-27-0)
- ((3R,4S)-4-phenylpyrrolidin-3-yl)methanol (CAS 848307-24-4)
- Tert-butyl (3-((6-chloropyrazin-2-yl)amino)propyl)carbamate (CAS 1289176-55-1)
- 10-Hydroxy-2-decenoic acid (CAS 14113-05-4)
- 4-Fluoro-2-(4-methoxybenzyl)phenol (CAS 1426-54-6)
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- Natural rubber (CAS 9006-04-6)
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