3-Amino-N-(2,3-dichlorophenyl)-4-(2-methoxyphenyl)-6-(p-tolyl)thieno[2,3-b]pyridine-2-carboxamide CAS 444153-49-5
| CAS No. | 444153-49-5 |
| Molecular Formula | C28H21Cl2N3O2S |
| Molecular Weight | 534.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
3-Amino-N-(2,3-dichlorophenyl)-4-(2-methoxyphenyl)-6-(p-tolyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 444153-49-5), molecular formula C28H21Cl2N3O2S and molecular weight 534.46 g/mol, is a CATO reference standard with documented purity and traceability.
3-Amino-N-(2,3-dichlorophenyl)-4-(2-methoxyphenyl)-6-(p-tolyl)thieno[2,3-b]pyridine-2-carboxamide (C28H21Cl2N3O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 3-Amino-N-(2,3-dichlorophenyl)-4-(2-methoxyphenyl)-6-(p-tolyl)thieno[2,3-b]pyridine-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C28H21Cl2N3O2S |
| Molecular Weight | 534.46 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 3-Amino-N-(2,3-dichlorophenyl)-4-(4-methoxyphenyl)-6-(p-tolyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 444153-43-9)
- Ethyl 6-amino-4-(2-chlorophenyl)-5-cyano-2-[({3-cyano-5H,6H,7H,8H,9H,10H-cycloocta[b]pyridin-2-yl}sulfanyl)methyl]-4H-pyran-3-carboxylate (CAS 316358-94-8)
- Ethyl 6-amino-4-(4-chlorophenyl)-5-cyano-2-(((3-cyano-5,6,7,8,9,10-hexahydrocycloocta[b]pyridin-2-yl)thio)methyl)-4H-pyran-3-carboxylate (CAS 339163-49-4)
- 3-Amino-4-(4-methoxyphenyl)-6-(p-tolyl)-N-(2-(trifluoromethyl)phenyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 332155-24-5)
- 3-Amino-N-(2-chlorobenzyl)-6-(3,4-dimethoxybenzyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 939889-17-5)
- 4-Amino-2-methylbenzene-1-sulfonyl fluoride (CAS 21320-92-3)
- (S)-2,2',2''-(10-(2-((5-Amino-5-carboxypentyl)amino)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetic acid (CAS 508172-24-5)
- 5-Amino-6-chloro-2-phenylpyridazin-3(2H)-one (CAS 1698-59-5)
Recommended Standards
- 2-((4-(2-Chlorophenyl)-6-(4-chlorophenyl)-3-cyanopyridin-2-yl)thio)-N-(4-ethoxyphenyl)acetamide (CAS 332372-36-8)
- Diquinoxalino[2,3-a:2',3'-c]phenazine-2,3,8,9,14,15-hexacarbonitrile (CAS 887401-68-5)
- Ruberythric acid (CAS 152-84-1)
- 9,9'-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-phenylene)bis(9H-carbazole) (CAS 1082549-89-0)
- 2-Ethyl-4-(trifluoromethyl)-2H-pyrazolo[3,4-b]pyridin-6(7H)-one (CAS 1018126-37-8)
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- 2-{2-[(chlorosulfonyl)methyl]phenyl}acetic acid (CAS 1547458-39-8)
- (S)-2-((tert-Butoxycarbonyl)amino)-5,5,5-trifluoropentanoic acid (CAS 453556-65-5)
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- 3-{[3-(Aminocarbonyl)piperidin-1-yl]carbonyl}-2,2-dimethylcyclopropanecarboxylic acid (CAS 1186653-79-1)
- 5-((4'-Methyl-[1,1'-biphenyl]-4-yl)oxy)furan-2-carbaldehyde (CAS 1291488-53-3)
- Liraglutide (14-31)TFA Salt (CAS CATO-C4X-19927)
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