2-((3-Cyano-5,6,7,8,9,10-hexahydrocycloocta[b]pyridin-2-yl)thio)-N-(4-methoxyphenyl)acetamide CAS 444160-96-7
| CAS No. | 444160-96-7 |
| Molecular Formula | C21H23N3O2S |
| Molecular Weight | 381.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-((3-Cyano-5,6,7,8,9,10-hexahydrocycloocta[b]pyridin-2-yl)thio)-N-(4-methoxyphenyl)acetamide (CAS 444160-96-7) is a high-purity analytical reference standard with the molecular formula C21H23N3O2S and a molecular weight of 381.49 g/mol.
The molecular framework of 2-((3-Cyano-5,6,7,8,9,10-hexahydrocycloocta[b]pyridin-2-yl)thio)-N-(4-methoxyphenyl)acetamide (C21H23N3O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-((3-Cyano-5,6,7,8,9,10-hexahydrocycloocta[b]pyridin-2-yl)thio)-N-(4-methoxyphenyl)acetamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H23N3O2S |
| Molecular Weight | 381.49 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Cyano Standards
- Ethyl 8-cyano-7-methoxy-2-((p-tolylthio)methyl)imidazo[1,2-a]pyridine-3-carboxylate (CAS 1704066-61-4)
- 2-Cyano-5-oxo-5-(2-thioxothiazolidin-3-yl)pentan-2-yl benzodithioate (CAS 887764-14-9)
- Ethyl 5-cyano-6-(4-(4-methoxyphenyl)piperazin-1-yl)-2-oxo-1,2-dihydropyridine-3-carboxylate (CAS 338396-66-0)
- 2-((7-Cyano-3,4-dihydro-2H-1,4-ethano-1,5-naphthyridin-6-yl)thio)-N-(4-fluorobenzyl)acetamide (CAS 728888-45-7)
- N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2-(4-phenylpiperazino)acetamide (CAS 838259-83-9)
- 2-[(3-Cyano-6-ethyl-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)sulfanyl]-N-(4-methoxyphenyl)acetamide (CAS 445222-25-3)
- N-(2-((3-Cyano-6-methylquinolin-2-yl)amino)ethyl)-4-methylbenzenesulfonamide (CAS 606105-57-1)
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Recommended Standards
- 1-{[2-(4-methoxyphenoxy)-1,3-thiazol-5-yl]methyl}-4-phenylpiperazine (CAS 439097-05-9)
- 2-((4-Ethyl-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(2-ethyl-6-methylphenyl)acetamide (CAS 577770-61-7)
- 1-(Azepan-1-yl)-2-((3-(p-tolyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)thio)ethan-1-one (CAS 852375-32-7)
- 2-((4-Ethyl-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(2-isopropylphenyl)acetamide (CAS 575462-79-2)
- 4-Methanesulfonyloxane-4-carboxylic acid (CAS 1247919-19-2)
- Dysprosium(III) acetate (CAS 18779-07-2)
- N-(4-Hydroxy-3-(methylthio)phenyl)methanesulfonamide (CAS 1243474-49-8)
- Diethylether (CAS 60-29-7)
- 1-Iodo-2-(methoxymethoxy)benzene (CAS 80778-47-8)
- (4-((4-Methyl-4H-1,2,4-triazol-3-yl)sulfonyl)piperidin-1-yl)(thiophen-3-yl)methanone (CAS 1448079-04-6)
- 2-((6-Bromohexyl)oxy)isoindoline-1,3-dione (CAS 92296-02-1)
- 2-Fluoro-4-methyl-5-nitrobenzoic acid (CAS 753924-40-2)
- 4-((3-Bromopropyl)amino)-5-chloropyridazin-3(2H)-one (CAS 252031-70-2)
- Semaglutide Impurity 151 xTFA (CAS CATO-C4X-2226151)
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