2-[(3-Cyano-6-ethyl-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)sulfanyl]-N-(4-methoxyphenyl)acetamide CAS 445222-25-3
| CAS No. | 445222-25-3 |
| Molecular Formula | C20H22N4O2S |
| Molecular Weight | 382.48 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 382.48 g/mol gives 2-[(3-Cyano-6-ethyl-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)sulfanyl]-N-(4-methoxyphenyl)acetamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-[(3-Cyano-6-ethyl-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)sulfanyl]-N-(4-methoxyphenyl)acetamide (CAS 445222-25-3) is a high-purity analytical reference standard with the molecular formula C20H22N4O2S and a molecular weight of 382.48 g/mol.
Structurally, 2-[(3-Cyano-6-ethyl-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)sulfanyl]-N-(4-methoxyphenyl)acetamide (C20H22N4O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 382.48 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H22N4O2S |
| Molecular Weight | 382.48 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Cyano Standards
- 2-((7-Cyano-3,4-dihydro-2H-1,4-ethano-1,5-naphthyridin-6-yl)thio)-N-(4-fluorobenzyl)acetamide (CAS 728888-45-7)
- Ethyl 5-cyano-6-(4-(4-methoxyphenyl)piperazin-1-yl)-2-oxo-1,2-dihydropyridine-3-carboxylate (CAS 338396-66-0)
- 2-{[3-cyano-6-(furan-2-yl)-4-(trifluoromethyl)pyridin-2-yl]sulfanyl}-N,N-diethylacetamide (CAS 625369-83-7)
- 4-Cyano-3,5-difluorophenyl 4-((1s,4r)-4-propylcyclohexyl)benzoate (CAS 186320-72-9)
- 2-((3-Cyano-5,6,7,8,9,10-hexahydrocycloocta[b]pyridin-2-yl)thio)-N-(4-methoxyphenyl)acetamide (CAS 444160-96-7)
- 4'-Cyano-[1,1'-biphenyl]-4-yl 4-hexylbenzoate (CAS 59443-81-1)
- Ethyl 8-cyano-7-methoxy-2-((p-tolylthio)methyl)imidazo[1,2-a]pyridine-3-carboxylate (CAS 1704066-61-4)
- N-(3-((8-Cyano-4-(phenylamino)pyrazolo[1,5-a][1,3,5]triazin-2-yl)amino)phenyl)acetamide (CAS 948575-39-1)
Recommended Standards
- 2,3-Dibromo-3-(3-chlorophenyl)-1-(2-methyloxiran-2-yl)propan-1-one (CAS 95639-66-0)
- 2-Amino-N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1h-pyrazol-4-yl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide (CAS 258843-88-8)
- 2-(1-(3-Methoxyphenyl)ethylidene)malononitrile (CAS 86604-43-5)
- 2-Benzyl-3-((2-morpholino-2-oxoethyl)thio)isoindolin-1-one (CAS 866008-87-9)
- 1,8-Octanediol (CAS 629-41-4)
- (S)-3-((tert-Butoxycarbonyl)amino)-4,4,4-trifluorobutanoic acid (CAS 1310680-43-3)
- (3R,4R)-4-(4-bromophenoxy)tetrahydrofuran-3-amine (CAS 1258963-55-1)
- Methyl 5-(4-amino-2-methylphenyl)furan-2-carboxylate (CAS 886494-28-6)
- N-(3-Cyclopropoxy-6-(methylamino)pyridin-2-yl)methanesulfonamide (CAS 1243481-73-3)
- 2-Butylthiazole-4-carboxylic acid (CAS 62657-88-9)
- 2-Chloro-N-(3-methyl-1,2,4-oxadiazol-5-yl)acetamide (CAS 1181505-87-2)
- 933789-97-0 35-Amino-3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacontan-1-ol MFCD11041097 (CAS 933789-97-0)
- 4-Ethyl-4-phenyloxazolidine-2,5-dione (CAS 52264-75-2)
- Semaglutide Impurity 7 (CAS CATO-C4X-22267)
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