5-Bromo-1-(2,6-dichlorophenyl)-7-methoxy-3,4-dihydroquinazolin-2-one CAS 444663-79-0
| CAS No. | 444663-79-0 |
| Molecular Formula | C15H11BrCl2N2O2 |
| Molecular Weight | 402.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Bromo-1-(2,6-dichlorophenyl)-7-methoxy-3,4-dihydroquinazolin-2-one is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-Bromo-1-(2,6-dichlorophenyl)-7-methoxy-3,4-dihydroquinazolin-2-one (CAS 444663-79-0) is a high-purity analytical reference standard with the molecular formula C15H11BrCl2N2O2 and a molecular weight of 402.07 g/mol.
The molecular framework of 5-Bromo-1-(2,6-dichlorophenyl)-7-methoxy-3,4-dihydroquinazolin-2-one (C15H11BrCl2N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Bromo-1-(2,6-dichlorophenyl)-7-methoxy-3,4-dihydroquinazolin-2-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H11BrCl2N2O2 |
| Molecular Weight | 402.07 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
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Recommended Standards
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- Ethyl 8-chloroquinoline-3-carboxylate (CAS 71083-19-7)
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- 3-(2,4-Dimethylphenyl)-1-(3,4-dimethylphenyl)propan-1-one (CAS 898794-14-4)
- tert-Butyl 3,6-diazabicyclo[3.1.1]heptane-3-carboxylate (CAS 1251017-66-9)
- cis-4-(3-Methoxybenzoyl)cyclohexane-1-carboxylic acid (CAS 735269-93-9)
- (4-(6-Aminopyrazin-2-yl)phenyl)methanol (CAS 1365969-34-1)
- Tert-butyl 6'-bromo-4'-oxospiro[azetidine-3,2'-chromane]-1-carboxylate (CAS 1291076-37-3)
- [(3-Phenoxyphenyl)methyl](propan-2-yl)amine hydrochloride (CAS 1240566-33-9)
- 4-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile (CAS 863868-32-0)
- Des-Ala35-Tirzepatide (CAS CATO-CPTD788939)
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