Anagrelide Impurity 21 CAS 17700-09-3
| CAS No. | 17700-09-3 |
| Molecular Formula | C6H2Cl3NO2 |
| Molecular Weight | 226.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Anagrelide Impurity 21 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Anagrelide Impurity 21 (CAS 17700-09-3) is a certified pharmaceutical impurity reference standard with the molecular formula C6H2Cl3NO2 and a molecular weight of 226.44 g/mol.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Anagrelide Impurity 21 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 226.44 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C6H2Cl3NO2 |
| Molecular Weight | 226.44 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Anagrelide Standards
- Anagrelide Impurity 22 (CAS 20098-48-0)
- Anagrelide Impurity 1 (CAS 70380-49-3)
- Anagrelide Impurity 20 (CAS 2112-22-3)
- Anagrelide Impurity 26 (CAS 444904-63-6)
- Anagrelide Impurity 6 (CAS 349150-82-9)
- Anagrelide Impurity 13 (CAS CATO-C4X-224013)
- Anagrelide Impurity 9 (CAS 28165-60-8)
- Anagrelide Impurity 37 (CAS CATO-C4X-224037)
Recommended Standards
- 2,3,5-trichloropyridine-4-carboxylic acid 4-Carboxy-2,3,5-trichloropyridine 406676-18-4 (CAS 406676-18-4)
- 3,5,6-trichloropyridine-2-carboxylic acid 40360-44-9 ACT10375 (CAS 40360-44-9)
- 2,2,4,4,6,8,8-Heptamethylnonane (CAS 4390-04-9)
- Avatrombopag Impurity 31 (CAS 69422-72-6)
- Ecabet Impurity 2 (CAS CATO-C4X-16262)
- Upadacitinib Impurity 63 (CAS CATO-C4X-240563)
- Roxadustat Impurity 102 (CAS CATO-C4X-2213102)
- 6-Bromo-2,2-difluorobenzo[d][1,3]dioxole-5-carboxylic acid (CAS 2451905-09-0)
- (R)-2-([1,1'-biphenyl]-4-ylmethyl)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid (CAS 959576-43-3)
- Methyl 3-amino-4,4,4-trifluorobutyrate (CAS 748746-28-3)
- 1-Fluoro-4-tosylbenzene (CAS 1643-97-6)
- 1-Pivaloyl-1H-imidazol (CAS 4195-19-1)
- 1-(3-Chloropropyl)-4-(2-methoxyphenyl)-piperazine x 2 HCl, 98% (CAS 21279-77-6)
- Glucagon (19-29) (human, rat, porcine) (CAS 64790-15-4)
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